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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF169
All Species:
13.03
Human Site:
T218
Identified Species:
35.83
UniProt:
Q8NCN4
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCN4
NP_001092108.1
708
77194
T218
L
L
P
E
D
T
E
T
G
K
R
K
M
D
E
Chimpanzee
Pan troglodytes
XP_522106
742
80950
T252
L
L
P
E
D
T
E
T
G
K
R
K
M
D
E
Rhesus Macaque
Macaca mulatta
XP_001082831
752
82300
T261
L
L
P
E
D
T
E
T
G
K
R
K
M
D
E
Dog
Lupus familis
XP_851632
770
83710
T280
L
L
S
E
D
M
E
T
G
K
R
K
M
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80XJ2
565
64761
E103
E
S
K
E
I
I
D
E
C
Q
P
V
R
R
L
Rat
Rattus norvegicus
XP_001066540
697
75850
V208
I
L
Q
E
D
S
E
V
G
K
R
K
A
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417246
533
59812
K71
K
D
E
S
L
V
L
K
V
N
Q
E
C
F
P
Frog
Xenopus laevis
Q6INS5
557
62872
G94
E
C
Q
R
R
A
S
G
Q
E
S
D
D
L
A
Zebra Danio
Brachydanio rerio
Q7T308
474
53229
V12
S
E
V
D
R
G
P
V
E
E
S
S
G
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
90.8
79.8
N.A.
20
78.5
N.A.
N.A.
47.7
20.6
21
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.1
92.2
84
N.A.
36
85.5
N.A.
N.A.
57.4
36.4
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
6.6
66.6
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
20
80
N.A.
N.A.
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
12
% A
% Cys:
0
12
0
0
0
0
0
0
12
0
0
0
12
0
0
% C
% Asp:
0
12
0
12
56
0
12
0
0
0
0
12
12
56
12
% D
% Glu:
23
12
12
67
0
0
56
12
12
23
0
12
0
0
45
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
0
12
0
12
56
0
0
0
12
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
12
12
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
12
0
0
0
0
12
0
56
0
56
0
0
0
% K
% Leu:
45
56
0
0
12
0
12
0
0
0
0
0
0
12
23
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
45
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
0
34
0
0
0
12
0
0
0
12
0
0
0
12
% P
% Gln:
0
0
23
0
0
0
0
0
12
12
12
0
0
0
0
% Q
% Arg:
0
0
0
12
23
0
0
0
0
0
56
0
12
12
0
% R
% Ser:
12
12
12
12
0
12
12
0
0
0
23
12
0
0
0
% S
% Thr:
0
0
0
0
0
34
0
45
0
0
0
0
0
0
0
% T
% Val:
0
0
12
0
0
12
0
23
12
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _