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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC44A5 All Species: 10.3
Human Site: S12 Identified Species: 20.61
UniProt: Q8NCS7 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NCS7 NP_001123530.1 719 81694 S12 E K P A D T P S E E E D F G D
Chimpanzee Pan troglodytes XP_001167809 719 81630 S12 E K P A D T P S E E E D F G D
Rhesus Macaque Macaca mulatta XP_001100356 719 81720 S12 E K P A D T A S E E E D F G D
Dog Lupus familis XP_547329 709 80598 R12 R V G C V R M R V N Q I L S S
Cat Felis silvestris
Mouse Mus musculus Q5RJI2 710 81410 G12 R K P P S S Q G D P R R Y D P
Rat Rattus norvegicus B4F795 705 79878 H12 S Q H Y Y G K H G T P Q K Y D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426673 715 81291 Y12 G E A S A P P Y G E P R K F D
Frog Xenopus laevis Q6IP59 710 80675 A12 G K S P P D S A Y G E P K K Y
Zebra Danio Brachydanio rerio A5PMW0 702 79452 V13 D P T F R G P V Y N R G C T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VAP3 796 90611 G12 V E L M N K Y G E P L R Y D R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20026 771 87293 A65 N H V P D Q I A R F N V I K P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12412 539 60232
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.9 74.5 N.A. 69.2 53.2 N.A. N.A. 66.3 57 60.3 N.A. 32.1 N.A. 34.7 N.A.
Protein Similarity: 100 99.5 98.6 85.9 N.A. 83.8 72.8 N.A. N.A. 81.9 75 76.9 N.A. 51.2 N.A. 54.3 N.A.
P-Site Identity: 100 100 93.3 0 N.A. 13.3 6.6 N.A. N.A. 20 13.3 13.3 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 100 93.3 6.6 N.A. 33.3 13.3 N.A. N.A. 33.3 20 20 N.A. 26.6 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 25 9 0 9 17 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 9 0 0 0 34 9 0 0 9 0 0 25 0 17 50 % D
% Glu: 25 17 0 0 0 0 0 0 34 34 34 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 9 0 0 25 9 0 % F
% Gly: 17 0 9 0 0 17 0 17 17 9 0 9 0 25 0 % G
% His: 0 9 9 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 0 0 0 9 9 0 0 % I
% Lys: 0 42 0 0 0 9 9 0 0 0 0 0 25 17 0 % K
% Leu: 0 0 9 0 0 0 0 0 0 0 9 0 9 0 0 % L
% Met: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 9 0 0 0 0 17 9 0 0 0 0 % N
% Pro: 0 9 34 25 9 9 34 0 0 17 17 9 0 0 17 % P
% Gln: 0 9 0 0 0 9 9 0 0 0 9 9 0 0 0 % Q
% Arg: 17 0 0 0 9 9 0 9 9 0 17 25 0 0 9 % R
% Ser: 9 0 9 9 9 9 9 25 0 0 0 0 0 9 9 % S
% Thr: 0 0 9 0 0 25 0 0 0 9 0 0 0 9 0 % T
% Val: 9 9 9 0 9 0 0 9 9 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 9 0 9 9 17 0 0 0 17 9 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _