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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC44A5
All Species:
18.48
Human Site:
S229
Identified Species:
36.97
UniProt:
Q8NCS7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCS7
NP_001123530.1
719
81694
S229
N
K
L
L
D
A
K
S
L
G
L
K
V
F
E
Chimpanzee
Pan troglodytes
XP_001167809
719
81630
S229
N
K
L
L
D
A
K
S
L
G
L
K
V
F
E
Rhesus Macaque
Macaca mulatta
XP_001100356
719
81720
S229
N
K
L
L
D
A
K
S
L
G
L
K
V
F
E
Dog
Lupus familis
XP_547329
709
80598
D227
V
G
M
K
I
F
E
D
Y
A
T
T
W
Y
W
Cat
Felis silvestris
Mouse
Mus musculus
Q5RJI2
710
81410
T223
S
D
L
I
N
A
R
T
I
G
L
K
L
L
E
Rat
Rattus norvegicus
B4F795
705
79878
W232
F
E
D
Y
T
V
S
W
Y
W
I
V
I
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426673
715
81291
S225
N
N
V
L
D
A
R
S
V
G
M
K
I
F
E
Frog
Xenopus laevis
Q6IP59
710
80675
Q223
N
V
V
L
E
A
R
Q
V
A
M
K
I
F
E
Zebra Danio
Brachydanio rerio
A5PMW0
702
79452
S223
K
I
V
E
D
Y
A
S
C
W
Y
W
I
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VAP3
796
90611
L291
N
G
T
N
D
A
Q
L
L
G
E
K
I
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20026
771
87293
P299
K
S
V
V
E
D
Q
P
V
T
H
K
V
I
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12412
539
60232
G119
T
G
S
G
I
Y
D
G
V
N
T
G
T
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.9
74.5
N.A.
69.2
53.2
N.A.
N.A.
66.3
57
60.3
N.A.
32.1
N.A.
34.7
N.A.
Protein Similarity:
100
99.5
98.6
85.9
N.A.
83.8
72.8
N.A.
N.A.
81.9
75
76.9
N.A.
51.2
N.A.
54.3
N.A.
P-Site Identity:
100
100
100
0
N.A.
40
0
N.A.
N.A.
60
40
13.3
N.A.
46.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
20
N.A.
86.6
20
N.A.
N.A.
93.3
80
26.6
N.A.
60
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
59
9
0
0
17
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
50
9
9
9
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
9
17
0
9
0
0
0
9
0
0
0
59
% E
% Phe:
9
0
0
0
0
9
0
0
0
0
0
0
0
42
0
% F
% Gly:
0
25
0
9
0
0
0
9
0
50
0
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% H
% Ile:
0
9
0
9
17
0
0
0
9
0
9
0
42
9
9
% I
% Lys:
17
25
0
9
0
0
25
0
0
0
0
67
0
0
0
% K
% Leu:
0
0
34
42
0
0
0
9
34
0
34
0
9
17
9
% L
% Met:
0
0
9
0
0
0
0
0
0
0
17
0
0
0
0
% M
% Asn:
50
9
0
9
9
0
0
0
0
9
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
17
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
9
0
0
0
9
42
0
0
0
0
0
0
0
% S
% Thr:
9
0
9
0
9
0
0
9
0
9
17
9
9
0
0
% T
% Val:
9
9
34
9
0
9
0
0
34
0
0
9
34
17
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
17
0
9
9
0
9
% W
% Tyr:
0
0
0
9
0
17
0
0
17
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _