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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC44A5 All Species: 16.36
Human Site: T546 Identified Species: 32.73
UniProt: Q8NCS7 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NCS7 NP_001123530.1 719 81694 T546 R L K R T Q N T L S K F L Q C
Chimpanzee Pan troglodytes XP_001167809 719 81630 T546 R L K R T Q N T L S K F L Q C
Rhesus Macaque Macaca mulatta XP_001100356 719 81720 T546 R L K R T E N T L S K F L Q C
Dog Lupus familis XP_547329 709 80598 N536 R L K D P Q N N I S K F L Q C
Cat Felis silvestris
Mouse Mus musculus Q5RJI2 710 81410 S540 R L K K A Q N S A A Q F L H C
Rat Rattus norvegicus B4F795 705 79878 K534 R L K A A Q N K F A K F L M V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426673 715 81291 S542 K L K G T Q N S F T R F L L C
Frog Xenopus laevis Q6IP59 710 80675 K539 K L K G A D N K C A R F L L C
Zebra Danio Brachydanio rerio A5PMW0 702 79452 A529 K L K G A H N A F A R F L L C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VAP3 796 90611 A626 K L K K Y D N A V T R A I L C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20026 771 87293 K599 K L G K S Q N K A V K W F L M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12412 539 60232 A392 I G F L K W L A E Y F N H Y A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.9 74.5 N.A. 69.2 53.2 N.A. N.A. 66.3 57 60.3 N.A. 32.1 N.A. 34.7 N.A.
Protein Similarity: 100 99.5 98.6 85.9 N.A. 83.8 72.8 N.A. N.A. 81.9 75 76.9 N.A. 51.2 N.A. 54.3 N.A.
P-Site Identity: 100 100 93.3 73.3 N.A. 53.3 53.3 N.A. N.A. 53.3 40 40 N.A. 26.6 N.A. 26.6 N.A.
P-Site Similarity: 100 100 100 80 N.A. 80 60 N.A. N.A. 80 60 60 N.A. 66.6 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 34 0 0 25 17 34 0 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 75 % C
% Asp: 0 0 0 9 0 17 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % E
% Phe: 0 0 9 0 0 0 0 0 25 0 9 75 9 0 0 % F
% Gly: 0 9 9 25 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 9 9 0 % H
% Ile: 9 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % I
% Lys: 42 0 84 25 9 0 0 25 0 0 50 0 0 0 0 % K
% Leu: 0 92 0 9 0 0 9 0 25 0 0 0 75 42 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % M
% Asn: 0 0 0 0 0 0 92 9 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 59 0 0 0 0 9 0 0 34 0 % Q
% Arg: 50 0 0 25 0 0 0 0 0 0 34 0 0 0 0 % R
% Ser: 0 0 0 0 9 0 0 17 0 34 0 0 0 0 0 % S
% Thr: 0 0 0 0 34 0 0 25 0 17 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 9 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _