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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC44A5
All Species:
10
Human Site:
Y145
Identified Species:
20
UniProt:
Q8NCS7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCS7
NP_001123530.1
719
81694
Y145
D
K
S
Y
W
E
D
Y
R
Q
F
C
K
T
T
Chimpanzee
Pan troglodytes
XP_001167809
719
81630
Y145
D
K
S
Y
W
E
D
Y
R
Q
F
C
K
T
T
Rhesus Macaque
Macaca mulatta
XP_001100356
719
81720
Y145
D
K
S
H
W
E
D
Y
R
Q
F
C
K
T
T
Dog
Lupus familis
XP_547329
709
80598
P145
C
K
T
P
F
G
K
P
A
K
A
L
A
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5RJI2
710
81410
F142
Y
W
E
Y
Y
R
Q
F
C
K
A
K
A
K
P
Rat
Rattus norvegicus
B4F795
705
79878
V149
G
F
K
N
N
K
G
V
A
E
V
L
R
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426673
715
81291
Q142
D
Q
W
N
Y
F
K
Q
Y
C
K
P
G
F
N
Frog
Xenopus laevis
Q6IP59
710
80675
R142
D
Y
Y
K
Q
F
C
R
D
G
F
N
N
F
T
Zebra Danio
Brachydanio rerio
A5PMW0
702
79452
A143
N
N
P
Q
K
S
V
A
Q
V
L
R
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VAP3
796
90611
R149
E
E
H
K
A
Q
I
R
T
K
S
D
I
Q
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20026
771
87293
S200
E
I
Q
N
K
M
K
S
V
V
Y
C
T
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12412
539
60232
Q39
A
A
N
V
N
D
G
Q
T
P
Y
H
F
R
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.9
74.5
N.A.
69.2
53.2
N.A.
N.A.
66.3
57
60.3
N.A.
32.1
N.A.
34.7
N.A.
Protein Similarity:
100
99.5
98.6
85.9
N.A.
83.8
72.8
N.A.
N.A.
81.9
75
76.9
N.A.
51.2
N.A.
54.3
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
0
N.A.
N.A.
6.6
20
0
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
26.6
20
N.A.
N.A.
20
20
13.3
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
0
0
9
17
0
17
0
17
0
0
% A
% Cys:
9
0
0
0
0
0
9
0
9
9
0
34
0
0
0
% C
% Asp:
42
0
0
0
0
9
25
0
9
0
0
9
9
17
25
% D
% Glu:
17
9
9
0
0
25
0
0
0
9
0
0
0
9
0
% E
% Phe:
0
9
0
0
9
17
0
9
0
0
34
0
9
17
0
% F
% Gly:
9
0
0
0
0
9
17
0
0
9
0
0
9
0
9
% G
% His:
0
0
9
9
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
9
0
0
0
0
9
0
0
0
0
0
9
0
0
% I
% Lys:
0
34
9
17
17
9
25
0
0
25
9
9
25
9
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
9
17
0
0
9
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
9
25
17
0
0
0
0
0
0
9
9
0
9
% N
% Pro:
0
0
9
9
0
0
0
9
0
9
0
9
0
0
9
% P
% Gln:
0
9
9
9
9
9
9
17
9
25
0
0
0
17
9
% Q
% Arg:
0
0
0
0
0
9
0
17
25
0
0
9
9
9
0
% R
% Ser:
0
0
25
0
0
9
0
9
0
0
9
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
17
0
0
0
9
25
34
% T
% Val:
0
0
0
9
0
0
9
9
9
17
9
0
0
0
0
% V
% Trp:
0
9
9
0
25
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
9
25
17
0
0
25
9
0
17
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _