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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA1407
All Species:
12.42
Human Site:
S222
Identified Species:
30.37
UniProt:
Q8NCU4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCU4
NP_065868.1
936
110568
S222
I
E
K
T
L
K
K
S
A
F
L
E
A
Q
C
Chimpanzee
Pan troglodytes
XP_516659
934
110401
S222
I
E
K
T
L
K
K
S
A
F
L
E
A
Q
C
Rhesus Macaque
Macaca mulatta
XP_001107271
934
110185
S222
I
Q
K
T
L
K
K
S
A
F
L
E
A
Q
C
Dog
Lupus familis
XP_545104
915
107605
S222
M
E
K
I
Q
K
K
S
V
F
L
E
A
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
XP_920975
986
115451
A288
M
A
D
A
L
K
K
A
A
F
L
E
A
Q
S
Rat
Rattus norvegicus
XP_221452
917
106852
A220
V
E
S
A
L
K
K
A
A
F
L
E
A
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521453
831
94443
V221
L
Q
R
E
K
E
Q
V
A
T
E
K
P
M
D
Chicken
Gallus gallus
XP_416572
870
103540
E212
E
M
V
K
L
R
K
E
M
A
E
K
R
Q
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001009986
892
106662
E243
R
Q
E
A
Q
R
Q
E
E
L
I
Q
Q
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790811
924
108674
I235
I
Q
R
E
E
Q
M
I
R
E
E
M
T
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
92.9
74.3
N.A.
65.9
67.7
N.A.
35
39.8
N.A.
34.7
N.A.
N.A.
N.A.
N.A.
28.4
Protein Similarity:
100
98.5
96.1
82.3
N.A.
76.5
80.3
N.A.
49.8
61.1
N.A.
56.4
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
100
93.3
66.6
N.A.
60
73.3
N.A.
6.6
20
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
73.3
N.A.
73.3
86.6
N.A.
46.6
33.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
30
0
0
0
20
60
10
0
0
60
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
10
40
10
20
10
10
0
20
10
10
30
60
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
40
0
0
10
0
0
0
10
0
0
10
0
0
0
10
% I
% Lys:
0
0
40
10
10
60
70
0
0
0
0
20
0
0
0
% K
% Leu:
10
0
0
0
60
0
0
0
0
10
60
0
0
0
0
% L
% Met:
20
10
0
0
0
0
10
0
10
0
0
10
0
10
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
40
0
0
20
10
20
0
0
0
0
10
10
70
0
% Q
% Arg:
10
0
20
0
0
20
0
0
10
0
0
0
10
10
0
% R
% Ser:
0
0
10
0
0
0
0
40
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
30
0
0
0
0
0
10
0
0
10
0
10
% T
% Val:
10
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _