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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1407 All Species: 7.88
Human Site: S640 Identified Species: 19.26
UniProt: Q8NCU4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NCU4 NP_065868.1 936 110568 S640 G R S D S R N S L S G L R R K
Chimpanzee Pan troglodytes XP_516659 934 110401 S640 G R S D S R N S L S G L R R K
Rhesus Macaque Macaca mulatta XP_001107271 934 110185 N639 G S R S D S R N C L S G R K R
Dog Lupus familis XP_545104 915 107605 S639 R G N D S Q N S L S G P R R I
Cat Felis silvestris
Mouse Mus musculus XP_920975 986 115451 P710 S R T D C R K P L S A S R R T
Rat Rattus norvegicus XP_221452 917 106852 P641 S R A D S R K P L S P S K R T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521453 831 94443 E630 E R R R Q E I E E K R I Q R E
Chicken Gallus gallus XP_416572 870 103540 A595 P E P K N T K A A T Q G K R P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001009986 892 106662 K681 K Q R E V E R K K E E K R Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790811 924 108674 Q693 R Q K Q K E Q Q K L K E M Q E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 92.9 74.3 N.A. 65.9 67.7 N.A. 35 39.8 N.A. 34.7 N.A. N.A. N.A. N.A. 28.4
Protein Similarity: 100 98.5 96.1 82.3 N.A. 76.5 80.3 N.A. 49.8 61.1 N.A. 56.4 N.A. N.A. N.A. N.A. 50.2
P-Site Identity: 100 100 13.3 60 N.A. 46.6 46.6 N.A. 13.3 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 33.3 73.3 N.A. 53.3 60 N.A. 33.3 33.3 N.A. 33.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 10 10 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 50 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 10 0 10 0 30 0 10 10 10 10 10 0 0 20 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 30 10 0 0 0 0 0 0 0 0 30 20 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 10 % I
% Lys: 10 0 10 10 10 0 30 10 20 10 10 10 20 10 20 % K
% Leu: 0 0 0 0 0 0 0 0 50 20 0 20 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 10 0 10 0 30 10 0 0 0 0 0 0 0 % N
% Pro: 10 0 10 0 0 0 0 20 0 0 10 10 0 0 10 % P
% Gln: 0 20 0 10 10 10 10 10 0 0 10 0 10 20 10 % Q
% Arg: 20 50 30 10 0 40 20 0 0 0 10 0 60 70 10 % R
% Ser: 20 10 20 10 40 10 0 30 0 50 10 20 0 0 0 % S
% Thr: 0 0 10 0 0 10 0 0 0 10 0 0 0 0 20 % T
% Val: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _