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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAD2
All Species:
10.61
Human Site:
S181
Identified Species:
21.21
UniProt:
Q8NCV1
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCV1
NP_001138872.1
583
61755
S181
S
A
L
C
Y
I
R
S
Q
L
E
N
P
E
S
Chimpanzee
Pan troglodytes
XP_001151022
583
61853
S181
S
A
L
C
Y
I
R
S
Q
L
E
N
P
E
S
Rhesus Macaque
Macaca mulatta
XP_001112441
580
61214
S178
S
A
L
C
Y
I
R
S
Q
L
E
S
P
E
S
Dog
Lupus familis
XP_544931
746
81097
V314
S
F
V
M
S
V
V
V
D
G
Q
F
F
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5P4
478
51050
A108
L
T
H
E
Q
R
C
A
A
V
V
S
A
G
L
Rat
Rattus norvegicus
Q3KR54
619
67797
L204
A
K
L
A
L
D
E
L
L
Q
L
D
E
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513167
576
63778
L162
A
K
L
A
L
D
E
L
L
L
P
D
N
P
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q32NG0
586
64778
P170
E
L
L
L
H
E
D
P
A
L
I
D
S
E
N
Zebra Danio
Brachydanio rerio
XP_687183
517
57019
N147
K
F
A
D
W
H
K
N
R
V
T
A
L
C
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NII1
676
74960
T179
T
E
K
L
S
N
P
T
S
L
E
Q
P
T
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22618
495
55301
E125
E
E
K
T
T
F
F
E
M
L
R
E
H
T
Y
Sea Urchin
Strong. purpuratus
XP_781832
696
76860
A294
A
A
Q
A
A
L
I
A
L
F
D
M
N
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.1
25.2
N.A.
61.7
29.2
N.A.
28.2
N.A.
25
33.6
N.A.
22.4
N.A.
21.2
24.5
Protein Similarity:
100
99.4
96.4
40.3
N.A.
68.9
45.5
N.A.
46.6
N.A.
43.8
49.2
N.A.
39.5
N.A.
37.3
40
P-Site Identity:
100
100
93.3
13.3
N.A.
0
6.6
N.A.
13.3
N.A.
20
0
N.A.
20
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
20
20
N.A.
26.6
N.A.
40
40
N.A.
33.3
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
34
9
25
9
0
0
17
17
0
0
9
9
0
0
% A
% Cys:
0
0
0
25
0
0
9
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
9
0
17
9
0
9
0
9
25
0
0
0
% D
% Glu:
17
17
0
9
0
9
17
9
0
0
34
9
9
42
17
% E
% Phe:
0
17
0
0
0
9
9
0
0
9
0
9
9
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
9
% G
% His:
0
0
9
0
9
9
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
25
9
0
0
0
9
0
0
0
0
% I
% Lys:
9
17
17
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
9
50
17
17
9
0
17
25
59
9
0
9
0
9
% L
% Met:
0
0
0
9
0
0
0
0
9
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
9
0
0
0
17
17
0
9
% N
% Pro:
0
0
0
0
0
0
9
9
0
0
9
0
34
25
0
% P
% Gln:
0
0
9
0
9
0
0
0
25
9
9
9
0
0
0
% Q
% Arg:
0
0
0
0
0
9
25
0
9
0
9
0
0
0
0
% R
% Ser:
34
0
0
0
17
0
0
25
9
0
0
17
9
0
25
% S
% Thr:
9
9
0
9
9
0
0
9
0
0
9
0
0
17
9
% T
% Val:
0
0
9
0
0
9
9
9
0
17
9
0
0
0
9
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _