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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADAD2 All Species: 13.03
Human Site: T436 Identified Species: 26.06
UniProt: Q8NCV1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NCV1 NP_001138872.1 583 61755 T436 D S C H D P P T L S R A I H T
Chimpanzee Pan troglodytes XP_001151022 583 61853 T436 D S C H D P P T L S R A I H T
Rhesus Macaque Macaca mulatta XP_001112441 580 61214 T433 D S C H D P P T L S R A I H T
Dog Lupus familis XP_544931 746 81097 S594 F S S I I L G S L Y H G D H L
Cat Felis silvestris
Mouse Mus musculus Q9D5P4 478 51050 R334 H D P S T L N R V I H S R P R
Rat Rattus norvegicus Q3KR54 619 67797 T466 G D G N C N D T R G L E I A I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513167 576 63778 A429 D T R G L E I A I K Q R V D D
Chicken Gallus gallus
Frog Xenopus laevis Q32NG0 586 64778 G435 A A C S D T R G L E I A V K Q
Zebra Danio Brachydanio rerio XP_687183 517 57019 N373 E K V S E I I N K R L G T G W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NII1 676 74960 V523 P V Y L H S I V L G S L L H P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22618 495 55301 S351 R L R K A V Y S R A A T F K P
Sea Urchin Strong. purpuratus XP_781832 696 76860 S548 I S S I I L G S L Y H G D H L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.1 25.2 N.A. 61.7 29.2 N.A. 28.2 N.A. 25 33.6 N.A. 22.4 N.A. 21.2 24.5
Protein Similarity: 100 99.4 96.4 40.3 N.A. 68.9 45.5 N.A. 46.6 N.A. 43.8 49.2 N.A. 39.5 N.A. 37.3 40
P-Site Identity: 100 100 100 20 N.A. 0 13.3 N.A. 6.6 N.A. 26.6 0 N.A. 13.3 N.A. 0 20
P-Site Similarity: 100 100 100 26.6 N.A. 13.3 20 N.A. 33.3 N.A. 40 13.3 N.A. 20 N.A. 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 9 0 0 9 0 9 9 34 0 9 0 % A
% Cys: 0 0 34 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 34 17 0 0 34 0 9 0 0 0 0 0 17 9 9 % D
% Glu: 9 0 0 0 9 9 0 0 0 9 0 9 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 9 0 9 9 0 0 17 9 0 17 0 25 0 9 0 % G
% His: 9 0 0 25 9 0 0 0 0 0 25 0 0 50 0 % H
% Ile: 9 0 0 17 17 9 25 0 9 9 9 0 34 0 9 % I
% Lys: 0 9 0 9 0 0 0 0 9 9 0 0 0 17 0 % K
% Leu: 0 9 0 9 9 25 0 0 59 0 17 9 9 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 9 9 9 0 0 0 0 0 0 0 % N
% Pro: 9 0 9 0 0 25 25 0 0 0 0 0 0 9 17 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % Q
% Arg: 9 0 17 0 0 0 9 9 17 9 25 9 9 0 9 % R
% Ser: 0 42 17 25 0 9 0 25 0 25 9 9 0 0 0 % S
% Thr: 0 9 0 0 9 9 0 34 0 0 0 9 9 0 25 % T
% Val: 0 9 9 0 0 9 0 9 9 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 9 0 0 0 9 0 0 17 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _