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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KREMEN2
All Species:
20
Human Site:
S451
Identified Species:
44
UniProt:
Q8NCW0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCW0
NP_078783.1
462
48849
S451
Y
R
P
L
S
A
S
S
Q
S
S
L
R
S
L
Chimpanzee
Pan troglodytes
XP_523272
498
52857
S487
Y
R
P
L
S
A
S
S
Q
S
S
L
R
S
L
Rhesus Macaque
Macaca mulatta
P12545
810
90237
F799
V
Y
V
R
V
S
R
F
V
T
W
I
E
G
V
Dog
Lupus familis
XP_853395
609
65612
S598
Y
R
P
L
S
A
S
S
Q
S
S
L
R
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1S7
461
49152
S450
Y
R
P
L
S
A
S
S
Q
S
S
L
R
S
L
Rat
Rattus norvegicus
Q924S4
473
51851
S462
K
K
K
L
K
G
Q
S
Q
Q
D
D
R
N
P
Wallaby
Macropus eugenll
O18783
806
90963
A617
P
Q
W
V
L
T
A
A
H
C
L
E
R
S
Q
Platypus
Ornith. anatinus
XP_001517970
615
65703
S604
Y
R
P
L
S
A
S
S
Q
S
S
L
R
S
L
Chicken
Gallus gallus
XP_415211
452
50370
Q442
F
K
K
Q
L
R
S
Q
Q
D
D
C
N
P
L
Frog
Xenopus laevis
Q90Y90
452
50170
G441
I
F
P
K
K
L
K
G
Q
H
D
D
R
N
P
Zebra Danio
Brachydanio rerio
Q7SXB3
263
28758
P253
E
P
V
E
G
A
D
P
L
M
G
S
A
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.1
20.2
68.8
N.A.
87.4
37.4
20.6
59.5
37
37.6
22.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
78.9
29.7
70.6
N.A.
90.6
54.5
30.1
64.5
53.9
52.3
32
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
26.6
13.3
100
20
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
40
40
100
33.3
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
55
10
10
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
10
28
19
0
0
0
% D
% Glu:
10
0
0
10
0
0
0
0
0
0
0
10
10
0
0
% E
% Phe:
10
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
10
0
0
10
0
0
19
0
% G
% His:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
10
19
19
10
19
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
55
19
10
0
0
10
0
10
46
0
0
55
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
19
0
% N
% Pro:
10
10
55
0
0
0
0
10
0
0
0
0
0
10
19
% P
% Gln:
0
10
0
10
0
0
10
10
73
10
0
0
0
0
10
% Q
% Arg:
0
46
0
10
0
10
10
0
0
0
0
0
73
0
0
% R
% Ser:
0
0
0
0
46
10
55
55
0
46
46
10
0
55
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
10
% T
% Val:
10
0
19
10
10
0
0
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
46
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _