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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNRF1
All Species:
26.06
Human Site:
S220
Identified Species:
52.12
UniProt:
Q8ND25
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8ND25
NP_115644.1
227
23783
S220
S
W
F
E
V
N
R
S
C
P
E
H
P
A
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109563
278
29893
S271
S
W
F
E
V
N
R
S
C
P
E
H
P
A
D
Dog
Lupus familis
XP_854366
187
20677
S180
E
W
F
E
V
N
R
S
C
P
E
H
P
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91V17
227
23824
S220
S
W
F
E
V
N
R
S
C
P
E
H
P
A
D
Rat
Rattus norvegicus
XP_002725463
227
23854
S220
S
W
F
E
V
N
R
S
C
P
E
H
P
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512110
89
10164
Chicken
Gallus gallus
XP_418778
146
15603
S139
E
W
F
E
V
N
R
S
C
P
E
H
P
S
D
Frog
Xenopus laevis
Q66KG7
195
20714
C188
S
W
F
E
V
N
R
C
C
P
E
H
P
S
D
Zebra Danio
Brachydanio rerio
Q6P4U6
215
22857
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572359
303
31946
S296
R
W
F
E
V
N
R
S
C
P
E
H
P
G
D
Honey Bee
Apis mellifera
XP_624991
212
22738
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198564
213
21441
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
80.9
44.9
N.A.
99.1
98.6
N.A.
31.2
44.4
72.2
82.8
N.A.
37.6
38.7
N.A.
39.2
Protein Similarity:
100
N.A.
80.9
55.9
N.A.
99.1
98.6
N.A.
35.6
53.7
77.9
88.1
N.A.
47.1
50.2
N.A.
52.8
P-Site Identity:
100
N.A.
100
86.6
N.A.
100
100
N.A.
0
86.6
86.6
0
N.A.
86.6
0
N.A.
0
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
0
93.3
93.3
0
N.A.
86.6
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
9
67
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
67
% D
% Glu:
17
0
0
67
0
0
0
0
0
0
67
0
0
0
0
% E
% Phe:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
67
0
0
67
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% R
% Ser:
42
0
0
0
0
0
0
59
0
0
0
0
0
25
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _