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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNRF1
All Species:
16.36
Human Site:
Y172
Identified Species:
32.73
UniProt:
Q8ND25
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8ND25
NP_115644.1
227
23783
Y172
L
S
K
P
R
L
S
Y
N
D
D
V
L
T
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109563
278
29893
Y172
L
S
K
P
R
L
S
Y
N
G
R
I
Q
R
S
Dog
Lupus familis
XP_854366
187
20677
D135
P
R
I
T
Y
N
E
D
V
L
S
K
D
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91V17
227
23824
Y172
L
S
K
P
R
L
S
Y
N
D
D
V
L
T
K
Rat
Rattus norvegicus
XP_002725463
227
23854
Y172
L
S
K
P
R
L
S
Y
N
D
D
V
L
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512110
89
10164
V38
R
I
T
Y
N
E
D
V
L
S
K
D
A
G
E
Chicken
Gallus gallus
XP_418778
146
15603
D94
P
R
I
T
Y
N
E
D
V
L
S
K
D
T
G
Frog
Xenopus laevis
Q66KG7
195
20714
D142
K
P
R
L
S
Y
N
D
D
V
L
T
R
D
A
Zebra Danio
Brachydanio rerio
Q6P4U6
215
22857
V164
R
L
S
Y
N
D
D
V
L
S
R
D
A
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572359
303
31946
Y248
L
T
K
P
R
L
S
Y
N
E
D
V
L
S
D
Honey Bee
Apis mellifera
XP_624991
212
22738
I161
R
L
S
Y
N
E
D
I
L
S
D
E
K
G
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198564
213
21441
V162
R
I
V
Y
N
E
D
V
L
T
L
D
S
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
80.9
44.9
N.A.
99.1
98.6
N.A.
31.2
44.4
72.2
82.8
N.A.
37.6
38.7
N.A.
39.2
Protein Similarity:
100
N.A.
80.9
55.9
N.A.
99.1
98.6
N.A.
35.6
53.7
77.9
88.1
N.A.
47.1
50.2
N.A.
52.8
P-Site Identity:
100
N.A.
60
0
N.A.
100
100
N.A.
0
6.6
0
0
N.A.
73.3
6.6
N.A.
0
P-Site Similarity:
100
N.A.
66.6
0
N.A.
100
100
N.A.
6.6
6.6
20
6.6
N.A.
93.3
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
17
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
34
25
9
25
42
25
17
9
9
% D
% Glu:
0
0
0
0
0
25
17
0
0
9
0
9
0
0
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
0
0
34
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
17
0
0
0
0
9
0
0
0
9
0
0
0
% I
% Lys:
9
0
42
0
0
0
0
0
0
0
9
17
9
0
25
% K
% Leu:
42
17
0
9
0
42
0
0
34
17
17
0
34
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
34
17
9
0
42
0
0
0
0
0
0
% N
% Pro:
17
9
0
42
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
34
17
9
0
42
0
0
0
0
0
17
0
9
9
0
% R
% Ser:
0
34
17
0
9
0
42
0
0
25
17
0
9
9
9
% S
% Thr:
0
9
9
17
0
0
0
0
0
9
0
9
0
34
0
% T
% Val:
0
0
9
0
0
0
0
25
17
9
0
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
34
17
9
0
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _