KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNRF1
All Species:
14.85
Human Site:
Y37
Identified Species:
29.7
UniProt:
Q8ND25
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8ND25
NP_115644.1
227
23783
Y37
G
A
P
H
F
G
H
Y
R
T
G
G
G
A
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109563
278
29893
Y37
G
A
P
H
F
G
H
Y
R
T
G
G
G
A
M
Dog
Lupus familis
XP_854366
187
20677
Cat
Felis silvestris
Mouse
Mus musculus
Q91V17
227
23824
Y37
G
A
P
H
F
G
H
Y
R
T
G
G
G
A
M
Rat
Rattus norvegicus
XP_002725463
227
23854
Y37
G
A
P
H
F
G
H
Y
R
T
G
G
G
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512110
89
10164
Chicken
Gallus gallus
XP_418778
146
15603
Frog
Xenopus laevis
Q66KG7
195
20714
Zebra Danio
Brachydanio rerio
Q6P4U6
215
22857
A29
D
S
A
V
P
P
S
A
H
F
G
H
Y
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572359
303
31946
S113
Q
Q
Q
G
S
I
T
S
S
G
S
S
P
H
S
Honey Bee
Apis mellifera
XP_624991
212
22738
A26
S
T
G
A
N
E
T
A
M
Q
G
F
S
M
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198564
213
21441
T27
P
D
S
P
G
G
S
T
A
S
G
G
Y
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
80.9
44.9
N.A.
99.1
98.6
N.A.
31.2
44.4
72.2
82.8
N.A.
37.6
38.7
N.A.
39.2
Protein Similarity:
100
N.A.
80.9
55.9
N.A.
99.1
98.6
N.A.
35.6
53.7
77.9
88.1
N.A.
47.1
50.2
N.A.
52.8
P-Site Identity:
100
N.A.
100
0
N.A.
100
100
N.A.
0
0
0
6.6
N.A.
0
6.6
N.A.
20
P-Site Similarity:
100
N.A.
100
0
N.A.
100
100
N.A.
0
0
0
13.3
N.A.
0
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
9
9
0
0
0
17
9
0
0
0
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
34
0
0
0
0
9
0
9
0
0
0
% F
% Gly:
34
0
9
9
9
42
0
0
0
9
59
42
34
0
0
% G
% His:
0
0
0
34
0
0
34
0
9
0
0
9
0
9
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
34
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
34
9
9
9
0
0
0
0
0
0
9
0
9
% P
% Gln:
9
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
34
0
0
0
0
9
0
% R
% Ser:
9
9
9
0
9
0
17
9
9
9
9
9
9
0
17
% S
% Thr:
0
9
0
0
0
0
17
9
0
34
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _