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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C1orf131 All Species: 3.64
Human Site: S252 Identified Species: 8.89
UniProt: Q8NDD1 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.56
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NDD1 NP_689592.2 294 32766 S252 G Q E D R R K S K K K S A P S
Chimpanzee Pan troglodytes XP_514270 293 32587 S251 K G Q E D R K S K K K S A P S
Rhesus Macaque Macaca mulatta XP_001112872 298 33327 K256 G Q E D R K S K K K K S A P S
Dog Lupus familis XP_536347 327 36050 K285 G Q E D R K S K K K K S A P S
Cat Felis silvestris
Mouse Mus musculus Q8CIL4 281 31325 R239 G R G Q E D R R S K K S A P S
Rat Rattus norvegicus Q3KRF3 282 31811 R240 G R S Q E D R R S K K L A P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419588 260 29029 K219 K K D L K E R K A K R K R S V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001124266 239 27514 P198 K R R K E G K P R T E K S K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_499532 175 19491 V134 A P A K R G Y V N Y K D L K I
Sea Urchin Strong. purpuratus XP_001203277 274 32055 G230 K I Q L Q N K G F W T D K T Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.2 90.9 64.2 N.A. 62.9 62.9 N.A. N.A. 39.1 N.A. 35.7 N.A. N.A. N.A. 24.1 25.1
Protein Similarity: 100 98.6 92.9 73.3 N.A. 74.8 72.7 N.A. N.A. 55.4 N.A. 55 N.A. N.A. N.A. 35 45.2
P-Site Identity: 100 66.6 80 80 N.A. 46.6 40 N.A. N.A. 6.6 N.A. 6.6 N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: 100 80 86.6 86.6 N.A. 60 53.3 N.A. N.A. 40 N.A. 33.3 N.A. N.A. N.A. 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 0 0 10 0 0 0 60 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 30 10 20 0 0 0 0 0 20 0 0 0 % D
% Glu: 0 0 30 10 30 10 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 50 10 10 0 0 20 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 40 10 0 20 10 20 40 30 40 70 70 20 10 20 0 % K
% Leu: 0 0 0 20 0 0 0 0 0 0 0 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 0 0 0 10 0 0 0 0 0 60 10 % P
% Gln: 0 30 20 20 10 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 30 10 0 40 20 30 20 10 0 10 0 10 0 0 % R
% Ser: 0 0 10 0 0 0 20 20 20 0 0 50 10 10 60 % S
% Thr: 0 0 0 0 0 0 0 0 0 10 10 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _