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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAPD5 All Species: 5.15
Human Site: S457 Identified Species: 12.59
UniProt: Q8NDF8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.56
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NDF8 NP_001035375 572 63267 S457 S A T Q S S S S D V D S D A T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001083145 631 69610 D469 I V D T Q Q L D K C N N N L S
Dog Lupus familis XP_535307 641 70316 D479 I V D T Q Q L D K C N N N L S
Cat Felis silvestris
Mouse Mus musculus Q68ED3 633 69686 D471 I V D T Q Q L D K C N N N L S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507597 595 65171 S480 S A T Q S S S S D V D S D A T
Chicken Gallus gallus XP_414098 612 68264 D449 I V D N Q Q L D K C N N N L A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697115 653 72115 E505 T L L V E R E E L D E C N N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625041 539 61114 Y425 V T D E V I E Y R K W I K E T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796681 830 90879 L468 H M V A M N Q L P L P D N T A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53632 584 66012 H462 T N R C F E L H S A T F K D R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 90.1 86.2 N.A. 84.8 N.A. N.A. 72.7 59.7 N.A. 53.9 N.A. N.A. 45.6 N.A. 31.3
Protein Similarity: 100 N.A. 90.4 86.9 N.A. 87 N.A. N.A. 78.9 67.1 N.A. 64.3 N.A. N.A. 60.4 N.A. 42.8
P-Site Identity: 100 N.A. 0 0 N.A. 0 N.A. N.A. 100 0 N.A. 0 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 N.A. 26.6 26.6 N.A. 26.6 N.A. N.A. 100 20 N.A. 20 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 10 0 0 0 0 0 10 0 0 0 20 20 % A
% Cys: 0 0 0 10 0 0 0 0 0 40 0 10 0 0 0 % C
% Asp: 0 0 50 0 0 0 0 40 20 10 20 10 20 10 0 % D
% Glu: 0 0 0 10 10 10 20 10 0 0 10 0 0 10 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 40 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 40 10 0 0 20 0 0 % K
% Leu: 0 10 10 0 0 0 50 10 10 10 0 0 0 40 0 % L
% Met: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 10 0 10 0 0 0 0 40 40 60 10 10 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % P
% Gln: 0 0 0 20 40 40 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 10 0 0 10 0 0 0 0 0 10 % R
% Ser: 20 0 0 0 20 20 20 20 10 0 0 20 0 0 30 % S
% Thr: 20 10 20 30 0 0 0 0 0 0 10 0 0 10 30 % T
% Val: 10 40 10 10 10 0 0 0 0 20 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _