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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPEPL1 All Species: 16.36
Human Site: S19 Identified Species: 27.69
UniProt: Q8NDH3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NDH3 NP_078939.3 523 55861 S19 A G D S D P Q S R P L L L L G
Chimpanzee Pan troglodytes XP_525369 359 37700
Rhesus Macaque Macaca mulatta XP_001086311 463 49382 L16 E R Y Q P K A L E Q S G C W L
Dog Lupus familis XP_543071 397 42215
Cat Felis silvestris
Mouse Mus musculus Q6NSR8 524 55922 S19 A G D A D P Q S R P L L L L G
Rat Rattus norvegicus NP_001101276 412 43664
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511141 548 58651 S43 R G R A D P Q S R P A A A P R
Chicken Gallus gallus XP_417486 523 56072 S19 A G E A D P Q S R P L L V L G
Frog Xenopus laevis NP_001090314 521 55831 A19 A G D A D P Q A R P L L V L G
Zebra Danio Brachydanio rerio NP_001017688 525 55746 N19 A G D S E P Q N R P V L I V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650240 558 60151 T43 L G C S D P Q T H P V L I I G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34629 491 52431 S19 A V G D G L T S L I I V G K K
Sea Urchin Strong. purpuratus XP_780549 523 55941 N22 N S T S D P A N R S V L I V G
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001151608 535 57316 V19 L T E S D P L V N P V I I I G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.3 84.6 72 N.A. 94.6 74.3 N.A. 83.9 87.7 83.5 81.1 N.A. 58.4 N.A. 42.6 58.7
Protein Similarity: 100 67.8 85.8 74.1 N.A. 97.3 77 N.A. 89.2 94.4 92.1 90 N.A. 72.2 N.A. 56.5 74.9
P-Site Identity: 100 0 0 0 N.A. 93.3 0 N.A. 46.6 80 80 66.6 N.A. 53.3 N.A. 13.3 40
P-Site Similarity: 100 0 0 0 N.A. 100 0 N.A. 53.3 100 100 100 N.A. 80 N.A. 26.6 66.6
Percent
Protein Identity: N.A. 58.5 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 74.7 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 33.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 66.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 0 0 29 0 0 15 8 0 0 8 8 8 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 29 8 58 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 15 0 8 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 50 8 0 8 0 0 0 0 0 0 8 8 0 58 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 8 8 29 15 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 8 % K
% Leu: 15 0 0 0 0 8 8 8 8 0 29 50 15 29 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 15 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 8 65 0 0 0 58 0 0 0 8 0 % P
% Gln: 0 0 0 8 0 0 50 0 0 8 0 0 0 0 0 % Q
% Arg: 8 8 8 0 0 0 0 0 50 0 0 0 0 0 8 % R
% Ser: 0 8 0 36 0 0 0 36 0 8 8 0 0 0 0 % S
% Thr: 0 8 8 0 0 0 8 8 0 0 0 0 0 0 0 % T
% Val: 0 8 0 0 0 0 0 8 0 0 29 8 15 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _