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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPEPL1
All Species:
30.61
Human Site:
Y382
Identified Species:
51.79
UniProt:
Q8NDH3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDH3
NP_078939.3
523
55861
Y382
Q
G
I
A
T
G
K
Y
H
A
A
V
L
T
N
Chimpanzee
Pan troglodytes
XP_525369
359
37700
L240
G
K
Y
H
A
A
V
L
T
N
S
A
E
W
E
Rhesus Macaque
Macaca mulatta
XP_001086311
463
49382
A341
A
D
I
I
L
D
M
A
T
L
T
G
A
Q
G
Dog
Lupus familis
XP_543071
397
42215
P278
I
K
G
K
T
T
M
P
G
M
K
R
D
C
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6NSR8
524
55922
Y382
Q
G
I
A
T
G
K
Y
H
A
A
V
L
T
N
Rat
Rattus norvegicus
NP_001101276
412
43664
G293
V
K
A
G
Q
K
C
G
D
L
V
H
P
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511141
548
58651
Y407
Q
G
I
A
T
G
K
Y
H
A
A
V
L
T
N
Chicken
Gallus gallus
XP_417486
523
56072
Y382
Q
G
I
A
T
G
K
Y
H
A
A
V
L
T
N
Frog
Xenopus laevis
NP_001090314
521
55831
Y382
Q
S
I
A
T
G
K
Y
H
A
A
V
L
T
N
Zebra Danio
Brachydanio rerio
NP_001017688
525
55746
H382
Q
G
I
S
T
G
K
H
H
A
A
V
M
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650240
558
60151
Y426
Q
G
V
A
T
G
K
Y
H
G
A
I
L
T
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34629
491
52431
I357
E
T
L
K
A
T
T
I
F
D
M
A
T
L
T
Sea Urchin
Strong. purpuratus
XP_780549
523
55941
Y384
Q
G
I
S
T
G
K
Y
H
A
G
L
L
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151608
535
57316
Y397
Q
A
I
A
T
G
R
Y
H
A
A
V
L
T
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.3
84.6
72
N.A.
94.6
74.3
N.A.
83.9
87.7
83.5
81.1
N.A.
58.4
N.A.
42.6
58.7
Protein Similarity:
100
67.8
85.8
74.1
N.A.
97.3
77
N.A.
89.2
94.4
92.1
90
N.A.
72.2
N.A.
56.5
74.9
P-Site Identity:
100
0
6.6
6.6
N.A.
100
0
N.A.
100
100
93.3
80
N.A.
80
N.A.
0
80
P-Site Similarity:
100
6.6
6.6
6.6
N.A.
100
0
N.A.
100
100
93.3
100
N.A.
93.3
N.A.
13.3
93.3
Percent
Protein Identity:
N.A.
58.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
74.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
50
15
8
0
8
0
58
58
15
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
0
0
8
0
0
8
8
0
0
8
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
8
50
8
8
0
65
0
8
8
8
8
8
0
0
15
% G
% His:
0
0
0
8
0
0
0
8
65
0
0
8
0
0
0
% H
% Ile:
8
0
65
8
0
0
0
8
0
0
0
8
0
0
0
% I
% Lys:
0
22
0
15
0
8
58
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
8
0
8
0
0
8
0
15
0
8
58
15
0
% L
% Met:
0
0
0
0
0
0
15
0
0
8
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
65
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% P
% Gln:
65
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% R
% Ser:
0
8
0
15
0
0
0
0
0
0
8
0
0
0
0
% S
% Thr:
0
8
0
0
72
15
8
0
15
0
8
0
8
65
8
% T
% Val:
8
0
8
0
0
0
8
0
0
0
8
50
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
8
0
0
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _