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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICA1L
All Species:
7.88
Human Site:
S427
Identified Species:
15.76
UniProt:
Q8NDH6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDH6
NP_612477.3
482
54407
S427
E
E
S
E
L
C
L
S
H
T
D
N
Q
P
V
Chimpanzee
Pan troglodytes
XP_001172921
481
54158
S426
E
E
S
E
L
C
L
S
H
T
D
N
Q
P
V
Rhesus Macaque
Macaca mulatta
XP_001085831
472
53342
Q418
G
S
G
F
L
P
S
Q
L
L
D
Q
N
M
K
Dog
Lupus familis
XP_545600
481
53856
P426
G
G
L
E
V
P
L
P
H
T
D
D
Q
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3TY65
431
48141
L377
L
T
S
S
S
Q
F
L
P
S
Q
L
F
D
L
Rat
Rattus norvegicus
Q6RUG5
435
48626
L380
L
P
S
R
L
F
D
L
G
L
H
A
D
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508894
481
54258
T426
V
K
R
L
L
C
A
T
H
C
S
N
Q
S
H
Chicken
Gallus gallus
XP_418682
516
58625
A459
P
L
S
I
P
Q
P
A
Q
K
P
N
S
L
N
Frog
Xenopus laevis
NP_001080094
512
57900
P455
T
S
S
C
Q
A
A
P
P
A
N
S
S
N
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392866
545
62009
S484
P
P
N
I
L
K
Q
S
L
G
D
A
A
L
G
Nematode Worm
Caenorhab. elegans
P91124
430
48887
P376
F
D
T
S
S
F
V
P
P
I
L
P
P
P
K
Sea Urchin
Strong. purpuratus
XP_001198366
691
77094
A633
F
A
D
R
M
S
A
A
Q
Q
T
P
A
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
48.1
87.5
N.A.
73.6
72.4
N.A.
70.7
49.2
48.8
N.A.
N.A.
N.A.
35.7
32.5
34.4
Protein Similarity:
100
96.6
62.6
92.1
N.A.
79.4
79.2
N.A.
79.2
64.5
66.4
N.A.
N.A.
N.A.
53.5
48.7
48.6
P-Site Identity:
100
100
13.3
53.3
N.A.
6.6
13.3
N.A.
33.3
13.3
6.6
N.A.
N.A.
N.A.
20
6.6
0
P-Site Similarity:
100
100
13.3
66.6
N.A.
20
13.3
N.A.
46.6
20
20
N.A.
N.A.
N.A.
26.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
25
17
0
9
0
17
17
0
17
% A
% Cys:
0
0
0
9
0
25
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
0
9
0
0
0
42
9
9
9
0
% D
% Glu:
17
17
0
25
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
17
0
0
9
0
17
9
0
0
0
0
0
9
0
0
% F
% Gly:
17
9
9
0
0
0
0
0
9
9
0
0
0
17
9
% G
% His:
0
0
0
0
0
0
0
0
34
0
9
0
0
0
9
% H
% Ile:
0
0
0
17
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
9
0
0
0
9
0
0
0
0
17
% K
% Leu:
17
9
9
9
50
0
25
17
17
17
9
9
0
17
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
9
34
9
9
9
% N
% Pro:
17
17
0
0
9
17
9
25
25
0
9
17
9
34
9
% P
% Gln:
0
0
0
0
9
17
9
9
17
9
9
9
34
0
0
% Q
% Arg:
0
0
9
17
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
17
50
17
17
9
9
25
0
9
9
9
17
9
0
% S
% Thr:
9
9
9
0
0
0
0
9
0
25
9
0
0
0
0
% T
% Val:
9
0
0
0
9
0
9
0
0
0
0
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _