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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICA1L
All Species:
20.91
Human Site:
T109
Identified Species:
41.82
UniProt:
Q8NDH6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDH6
NP_612477.3
482
54407
T109
A
G
K
M
M
D
A
T
G
K
A
L
C
S
S
Chimpanzee
Pan troglodytes
XP_001172921
481
54158
T109
A
G
K
M
M
D
A
T
G
K
A
L
C
S
S
Rhesus Macaque
Macaca mulatta
XP_001085831
472
53342
K106
K
M
M
Q
A
T
G
K
A
L
C
F
S
S
Q
Dog
Lupus familis
XP_545600
481
53856
T109
A
G
K
M
M
D
A
T
G
K
A
L
C
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3TY65
431
48141
V67
Q
E
T
C
N
E
L
V
K
I
V
E
K
Y
Q
Rat
Rattus norvegicus
Q6RUG5
435
48626
V70
C
N
E
L
V
K
A
V
E
K
Y
Q
L
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508894
481
54258
T109
A
R
K
M
M
D
A
T
G
K
T
L
C
S
S
Chicken
Gallus gallus
XP_418682
516
58625
T118
A
G
K
M
M
Q
A
T
G
K
A
L
C
F
S
Frog
Xenopus laevis
NP_001080094
512
57900
T118
A
G
K
I
M
Q
A
T
G
K
A
L
C
F
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392866
545
62009
V126
A
G
K
M
M
T
A
V
G
K
S
L
S
Y
S
Nematode Worm
Caenorhab. elegans
P91124
430
48887
N66
N
E
L
D
T
C
L
N
L
Y
R
S
V
H
G
Sea Urchin
Strong. purpuratus
XP_001198366
691
77094
V224
A
G
K
M
M
A
A
V
G
K
A
Q
T
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
48.1
87.5
N.A.
73.6
72.4
N.A.
70.7
49.2
48.8
N.A.
N.A.
N.A.
35.7
32.5
34.4
Protein Similarity:
100
96.6
62.6
92.1
N.A.
79.4
79.2
N.A.
79.2
64.5
66.4
N.A.
N.A.
N.A.
53.5
48.7
48.6
P-Site Identity:
100
100
6.6
100
N.A.
0
13.3
N.A.
86.6
86.6
80
N.A.
N.A.
N.A.
66.6
0
73.3
P-Site Similarity:
100
100
6.6
100
N.A.
6.6
33.3
N.A.
86.6
86.6
86.6
N.A.
N.A.
N.A.
73.3
0
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
0
9
9
75
0
9
0
50
0
0
0
0
% A
% Cys:
9
0
0
9
0
9
0
0
0
0
9
0
50
0
0
% C
% Asp:
0
0
0
9
0
34
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
17
9
0
0
9
0
0
9
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
17
0
% F
% Gly:
0
59
0
0
0
0
9
0
67
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
9
0
67
0
0
9
0
9
9
75
0
0
9
0
0
% K
% Leu:
0
0
9
9
0
0
17
0
9
9
0
59
9
0
9
% L
% Met:
0
9
9
59
67
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
9
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
9
0
17
0
0
0
0
0
17
0
0
17
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
9
0
0
9
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
9
9
17
50
67
% S
% Thr:
0
0
9
0
9
17
0
50
0
0
9
0
9
0
0
% T
% Val:
0
0
0
0
9
0
0
34
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
9
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _