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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICA1L
All Species:
29.09
Human Site:
T145
Identified Species:
58.18
UniProt:
Q8NDH6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDH6
NP_612477.3
482
54407
T145
S
Q
R
A
V
S
D
T
L
M
T
I
N
R
M
Chimpanzee
Pan troglodytes
XP_001172921
481
54158
T145
S
Q
R
A
V
S
D
T
L
M
T
I
N
R
M
Rhesus Macaque
Macaca mulatta
XP_001085831
472
53342
L142
R
A
I
S
D
T
W
L
T
V
N
R
M
E
Q
Dog
Lupus familis
XP_545600
481
53856
T145
S
Q
R
A
V
S
D
T
L
M
T
I
N
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q3TY65
431
48141
G103
E
R
D
S
T
Q
A
G
E
M
M
D
A
A
G
Rat
Rattus norvegicus
Q6RUG5
435
48626
M106
A
T
Q
A
G
K
M
M
G
A
A
G
K
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508894
481
54258
T145
S
Q
R
A
V
S
D
T
L
V
T
I
N
R
M
Chicken
Gallus gallus
XP_418682
516
58625
T154
R
Y
R
A
I
S
D
T
W
L
T
V
N
R
M
Frog
Xenopus laevis
NP_001080094
512
57900
S154
R
Y
R
A
I
S
D
S
W
L
T
V
N
R
M
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392866
545
62009
T162
R
Q
R
A
I
E
D
T
L
Q
K
V
Q
A
M
Nematode Worm
Caenorhab. elegans
P91124
430
48887
Y102
V
Q
N
V
L
G
K
Y
L
K
E
K
G
K
I
Sea Urchin
Strong. purpuratus
XP_001198366
691
77094
T260
R
Y
R
A
I
S
D
T
L
M
T
I
N
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
48.1
87.5
N.A.
73.6
72.4
N.A.
70.7
49.2
48.8
N.A.
N.A.
N.A.
35.7
32.5
34.4
Protein Similarity:
100
96.6
62.6
92.1
N.A.
79.4
79.2
N.A.
79.2
64.5
66.4
N.A.
N.A.
N.A.
53.5
48.7
48.6
P-Site Identity:
100
100
0
100
N.A.
6.6
6.6
N.A.
93.3
60
53.3
N.A.
N.A.
N.A.
46.6
13.3
80
P-Site Similarity:
100
100
20
100
N.A.
20
26.6
N.A.
100
80
80
N.A.
N.A.
N.A.
60
33.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
75
0
0
9
0
0
9
9
0
9
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
0
67
0
0
0
0
9
0
0
0
% D
% Glu:
9
0
0
0
0
9
0
0
9
0
9
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
9
0
9
9
0
0
9
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
34
0
0
0
0
0
0
42
0
0
9
% I
% Lys:
0
0
0
0
0
9
9
0
0
9
9
9
9
9
0
% K
% Leu:
0
0
0
0
9
0
0
9
59
17
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
9
9
0
42
9
0
9
0
67
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
9
0
59
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
50
9
0
0
9
0
0
0
9
0
0
9
0
9
% Q
% Arg:
42
9
67
0
0
0
0
0
0
0
0
9
0
59
0
% R
% Ser:
34
0
0
17
0
59
0
9
0
0
0
0
0
0
0
% S
% Thr:
0
9
0
0
9
9
0
59
9
0
59
0
0
0
0
% T
% Val:
9
0
0
9
34
0
0
0
0
17
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% W
% Tyr:
0
25
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _