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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
41.82
Human Site:
S1089
Identified Species:
61.33
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
S1089
K
K
L
C
R
N
N
S
A
Q
A
F
L
S
P
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
S1089
K
K
L
C
R
N
D
S
A
Q
A
F
L
S
P
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
S1089
K
K
L
C
R
N
N
S
A
Q
A
F
L
S
P
Dog
Lupus familis
XP_538328
1235
143711
S1089
K
K
L
C
R
N
V
S
A
Q
A
F
L
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
S1088
K
K
L
C
R
N
N
S
A
Q
A
F
L
S
P
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
S1093
K
A
L
S
R
N
S
S
A
Q
A
F
L
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
S1060
K
L
L
C
R
N
N
S
A
Q
A
F
L
S
P
Chicken
Gallus gallus
Q90988
1189
134923
G1051
I
F
S
M
L
L
P
G
A
K
A
M
L
V
P
Frog
Xenopus laevis
O93308
1232
142609
S1093
K
A
L
S
R
N
S
S
A
Q
A
F
L
G
P
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
S1091
K
K
L
C
R
N
A
S
A
Q
A
I
L
S
A
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
S1096
K
R
L
C
R
N
S
S
A
Q
A
I
L
S
A
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
S1091
V
A
C
C
Q
H
I
S
D
A
I
D
G
I
Y
Honey Bee
Apis mellifera
XP_395059
1230
141414
K1092
P
I
Y
K
S
L
A
K
N
Q
S
A
Q
A
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
S1103
K
A
L
S
R
N
H
S
A
Q
A
F
L
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
L1078
T
R
K
Q
Y
D
E
L
R
K
R
R
L
D
E
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
N1087
R
E
L
T
K
N
P
N
S
N
V
E
L
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
93.3
100
93.3
N.A.
100
73.3
N.A.
93.3
26.6
73.3
80
73.3
13.3
6.6
N.A.
73.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
80
N.A.
93.3
33.3
80
80
86.6
26.6
20
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
0
0
0
13
0
75
7
75
7
0
13
13
% A
% Cys:
0
0
7
57
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
7
0
7
0
0
7
0
7
0
% D
% Glu:
0
7
0
0
0
0
7
0
0
0
0
7
0
0
7
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
57
0
0
7
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
0
7
19
7
% G
% His:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
0
0
0
7
0
0
0
7
13
0
7
0
% I
% Lys:
69
38
7
7
7
0
0
7
0
13
0
0
0
0
0
% K
% Leu:
0
7
75
0
7
13
0
7
0
0
0
0
88
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
75
25
7
7
7
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
13
0
0
0
0
0
0
0
63
% P
% Gln:
0
0
0
7
7
0
0
0
0
75
0
0
7
0
0
% Q
% Arg:
7
13
0
0
69
0
0
0
7
0
7
7
0
0
0
% R
% Ser:
0
0
7
19
7
0
19
75
7
0
7
0
0
50
0
% S
% Thr:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
0
0
7
0
0
0
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _