KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
10.62
Human Site:
S1234
Identified Species:
15.57
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
S1234
S
S
K
R
H
G
E
S
R
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
S1234
S
S
K
R
H
G
E
S
R
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
Dog
Lupus familis
XP_538328
1235
143711
S1234
N
S
K
R
N
H
E
S
R
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
P1233
G
S
R
S
H
R
K
P
R
V
P
R
V
S
M
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
A1205
G
S
R
S
S
C
R
A
G
N
G
Q
S
L
V
Chicken
Gallus gallus
Q90988
1189
134923
Frog
Xenopus laevis
O93308
1232
142609
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
R1241
E
K
Q
A
H
V
E
R
V
R
P
V
_
_
_
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
T1234
V
Y
I
M
D
L
T
T
F
E
D
T
_
_
_
Honey Bee
Apis mellifera
XP_395059
1230
141414
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
T1244
P
A
I
P
N
P
I
T
G
I
R
_
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
N1221
V
G
I
Y
K
T
D
N
C
T
K
S
I
T
I
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
100
0
66.6
N.A.
20
0
N.A.
6.6
0
0
0
16.6
0
0
N.A.
0
P-Site Similarity:
100
100
0
88.8
N.A.
33.3
0
N.A.
26.6
0
0
0
25
8.3
0
N.A.
36.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
7
0
0
0
7
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
25
0
0
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
13
7
0
0
0
13
0
0
13
0
7
0
0
0
0
% G
% His:
0
0
0
0
25
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
19
0
0
0
7
0
0
7
0
0
7
0
7
% I
% Lys:
0
7
19
0
7
0
7
0
0
0
7
0
0
0
0
% K
% Leu:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
7
0
0
0
13
0
0
7
0
7
0
0
0
0
0
% N
% Pro:
7
0
0
7
0
7
0
7
0
0
13
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
13
19
0
7
7
7
25
7
7
7
0
0
0
% R
% Ser:
13
32
0
13
7
0
0
19
0
0
0
7
7
7
0
% S
% Thr:
0
0
0
0
0
7
7
13
0
7
0
7
0
7
0
% T
% Val:
13
0
0
0
0
7
0
0
7
7
0
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
19
19
25
38
38
38
% _