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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
24.55
Human Site:
S370
Identified Species:
36
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
S370
R
D
I
E
L
E
A
S
Q
L
D
R
Y
K
E
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
S370
R
D
I
E
L
E
A
S
Q
L
D
R
Y
K
E
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
S370
R
D
I
E
L
E
A
S
Q
L
D
H
Y
K
E
Dog
Lupus familis
XP_538328
1235
143711
S370
R
D
I
E
L
E
A
S
Q
L
D
R
Y
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
S370
R
D
I
E
L
E
N
S
Q
L
D
R
Y
K
L
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
N370
R
D
L
T
L
E
E
N
Q
V
K
K
Y
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
N341
R
D
V
E
L
E
S
N
Q
L
E
Q
Y
K
E
Chicken
Gallus gallus
Q90988
1189
134923
S397
N
D
S
G
Q
G
T
S
L
A
D
Q
M
M
T
Frog
Xenopus laevis
O93308
1232
142609
N370
R
D
L
T
L
E
E
N
Q
V
K
K
Y
H
R
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
S370
A
G
V
Q
L
Q
E
S
Q
L
E
R
Y
K
E
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
D370
R
H
I
E
L
D
E
D
Q
L
K
Q
Y
R
D
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
G393
K
S
V
N
M
E
E
G
L
V
Q
E
Y
D
R
Honey Bee
Apis mellifera
XP_395059
1230
141414
E371
R
D
V
Q
L
E
D
E
Q
V
R
E
Y
N
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
S370
K
D
M
T
L
E
T
S
Q
V
T
E
Y
H
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
A425
S
E
L
T
K
I
R
A
E
L
E
P
W
E
K
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
D384
K
F
K
L
N
E
N
D
L
K
T
Y
N
C
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
40
N.A.
66.6
20
40
53.3
46.6
13.3
40
N.A.
40
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
66.6
N.A.
100
26.6
66.6
80
73.3
40
60
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
25
7
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
69
0
0
0
7
7
13
0
0
38
0
0
7
7
% D
% Glu:
0
7
0
44
0
75
32
7
7
0
19
19
0
7
32
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
7
0
7
0
7
0
0
0
0
0
0
7
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
7
0
19
0
% H
% Ile:
0
0
38
0
0
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
0
7
0
7
0
0
0
0
7
19
13
0
44
7
% K
% Leu:
0
0
19
7
75
0
0
0
19
57
0
0
0
0
13
% L
% Met:
0
0
7
0
7
0
0
0
0
0
0
0
7
7
0
% M
% Asn:
7
0
0
7
7
0
13
19
0
0
0
0
7
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
13
7
7
0
0
75
0
7
19
0
0
0
% Q
% Arg:
63
0
0
0
0
0
7
0
0
0
7
32
0
7
25
% R
% Ser:
7
7
7
0
0
0
7
50
0
0
0
0
0
0
7
% S
% Thr:
0
0
0
25
0
0
13
0
0
0
13
0
0
0
7
% T
% Val:
0
0
25
0
0
0
0
0
0
32
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
82
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _