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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
22.73
Human Site:
S918
Identified Species:
33.33
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
S918
E
V
V
S
I
Q
T
S
L
E
Q
K
R
L
E
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
S918
E
V
V
S
I
Q
T
S
L
E
Q
K
R
L
E
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
S918
E
V
V
I
T
Q
T
S
L
E
Q
K
R
L
E
Dog
Lupus familis
XP_538328
1235
143711
S918
E
V
V
I
I
Q
T
S
L
E
Q
K
R
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
S918
E
V
V
I
I
Q
G
S
L
E
Q
K
L
L
E
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
K918
E
V
T
A
I
E
T
K
L
E
Q
K
R
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
S889
E
V
V
A
I
E
A
S
L
E
Q
K
R
L
E
Chicken
Gallus gallus
Q90988
1189
134923
K895
D
I
K
A
K
S
A
K
I
E
K
Y
R
E
Q
Frog
Xenopus laevis
O93308
1232
142609
K918
E
V
T
A
I
E
T
K
L
E
Q
K
R
S
D
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
A920
Q
T
I
S
T
D
A
A
L
E
H
L
R
L
T
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
A926
E
V
M
S
A
E
T
A
L
E
Q
K
R
M
A
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
D920
D
I
S
K
A
R
K
D
V
A
N
L
A
K
E
Honey Bee
Apis mellifera
XP_395059
1230
141414
K920
Q
L
N
A
I
E
T
K
I
E
Q
K
K
A
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
K918
Q
I
T
A
N
E
T
K
L
E
Q
K
K
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
T917
K
A
F
E
I
Q
E
T
Y
K
K
T
Q
Q
L
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
V918
D
M
N
S
N
L
Q
V
L
K
R
E
R
D
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
100
86.6
93.3
N.A.
80
60
N.A.
80
13.3
60
33.3
60
6.6
40
N.A.
33.3
P-Site Similarity:
100
100
86.6
93.3
N.A.
80
80
N.A.
93.3
53.3
80
53.3
86.6
33.3
80
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
38
13
0
19
13
0
7
0
0
7
13
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
0
7
0
7
0
0
0
0
0
7
19
% D
% Glu:
57
0
0
7
0
38
7
0
0
82
0
7
0
7
50
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
19
7
19
57
0
0
0
13
0
0
0
0
0
0
% I
% Lys:
7
0
7
7
7
0
7
32
0
13
13
69
13
7
0
% K
% Leu:
0
7
0
0
0
7
0
0
75
0
0
13
7
44
7
% L
% Met:
0
7
7
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
13
0
13
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
19
0
0
0
0
38
7
0
0
0
69
0
7
7
7
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
7
0
69
0
0
% R
% Ser:
0
0
7
32
0
7
0
38
0
0
0
0
0
13
0
% S
% Thr:
0
7
19
0
13
0
57
7
0
0
0
7
0
0
7
% T
% Val:
0
57
38
0
0
0
0
7
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _