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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
25.76
Human Site:
S991
Identified Species:
37.78
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
S991
E
D
L
K
A
L
Q
S
D
Q
E
I
E
A
H
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
S991
E
D
L
K
A
L
Q
S
D
Q
E
I
E
A
H
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
S991
E
D
L
K
A
L
Q
S
D
Q
E
V
E
A
H
Dog
Lupus familis
XP_538328
1235
143711
S991
D
D
L
K
A
L
E
S
D
K
E
I
E
A
H
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
S990
E
D
L
K
A
L
Q
S
D
K
E
V
E
A
H
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
A995
E
D
L
K
D
A
Q
A
E
E
E
I
K
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
S962
E
D
L
K
E
L
R
S
D
K
E
V
Q
T
H
Chicken
Gallus gallus
Q90988
1189
134923
A959
D
T
T
Y
D
F
E
A
N
N
P
K
E
T
G
Frog
Xenopus laevis
O93308
1232
142609
A995
E
D
L
K
D
A
V
A
D
D
D
I
K
Q
E
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
E993
N
S
L
K
M
L
T
E
E
S
E
V
E
A
M
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
T998
A
E
L
R
S
V
Q
T
E
Q
E
A
E
A
C
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
N990
S
T
S
A
A
M
E
N
I
I
E
V
D
Y
S
Honey Bee
Apis mellifera
XP_395059
1230
141414
E998
E
N
L
K
D
I
E
E
E
D
I
K
K
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
G1006
H
S
L
R
E
L
D
G
S
E
I
K
E
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
L981
E
K
G
Y
K
K
K
L
N
D
L
Q
I
A
F
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
K987
I
N
Y
K
G
L
P
K
K
Y
K
E
N
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
100
93.3
80
N.A.
86.6
46.6
N.A.
60
6.6
40
40
40
13.3
20
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
73.3
N.A.
86.6
33.3
60
53.3
80
46.6
53.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
38
13
0
19
0
0
0
7
0
50
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
13
50
0
0
25
0
7
0
44
19
7
0
7
0
0
% D
% Glu:
57
7
0
0
13
0
25
13
25
13
63
7
57
7
13
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
7
0
7
0
0
7
0
0
0
0
0
0
7
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
38
% H
% Ile:
7
0
0
0
0
7
0
0
7
7
13
32
7
0
0
% I
% Lys:
0
7
0
69
7
7
7
7
7
19
7
19
19
0
0
% K
% Leu:
0
0
75
0
0
57
0
7
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
7
% M
% Asn:
7
13
0
0
0
0
0
7
13
7
0
0
7
7
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
38
0
0
25
0
7
7
13
0
% Q
% Arg:
0
0
0
13
0
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
7
13
7
0
7
0
0
38
7
7
0
0
0
0
7
% S
% Thr:
0
13
7
0
0
0
7
7
0
0
0
0
0
19
13
% T
% Val:
0
0
0
0
0
7
7
0
0
0
0
32
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
13
0
0
0
0
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _