KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
17.88
Human Site:
T280
Identified Species:
26.22
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
T280
L
T
R
Q
L
Q
Q
T
E
K
E
L
K
S
V
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
T280
L
T
R
Q
L
Q
Q
T
E
K
E
I
K
S
V
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
T280
L
T
R
Q
L
Q
Q
T
E
K
E
L
K
S
L
Dog
Lupus familis
XP_538328
1235
143711
T280
L
T
R
Q
L
Q
Q
T
E
K
E
L
K
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
T280
L
T
R
Q
L
Q
Q
T
A
K
E
L
K
S
V
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
I280
M
M
R
E
Q
Q
Q
I
E
K
E
I
K
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
M251
R
T
R
E
V
Q
Q
M
E
K
E
Y
K
T
L
Chicken
Gallus gallus
Q90988
1189
134923
L277
N
E
K
K
V
K
E
L
A
Q
Q
I
E
E
T
Frog
Xenopus laevis
O93308
1232
142609
I280
M
M
R
E
Q
Q
A
I
E
K
E
I
K
E
K
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
L280
L
N
R
E
L
Q
Q
L
E
K
E
I
R
S
Q
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
L280
L
N
R
E
Q
Q
H
L
E
K
E
I
R
A
Q
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
I303
I
T
R
D
L
A
K
I
D
Q
E
I
R
E
F
Honey Bee
Apis mellifera
XP_395059
1230
141414
I281
L
G
R
D
L
A
K
I
E
Q
D
I
R
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
I280
L
T
R
E
L
A
A
I
E
K
D
T
R
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
R317
V
H
E
K
H
K
K
R
Q
E
V
L
D
N
E
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
Q294
E
S
A
V
I
S
K
Q
K
S
K
L
D
Y
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
46.6
N.A.
53.3
0
40
60
40
26.6
33.3
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
93.3
66.6
N.A.
80
60
60
80
66.6
66.6
66.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
19
13
0
13
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
0
0
0
0
7
0
13
0
13
0
0
% D
% Glu:
7
7
7
38
0
0
7
0
69
7
69
0
7
38
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
0
7
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
7
0
0
32
0
0
0
50
0
0
7
% I
% Lys:
0
0
7
13
0
13
25
0
7
69
7
0
50
0
19
% K
% Leu:
57
0
0
0
57
0
0
19
0
0
0
38
0
0
19
% L
% Met:
13
13
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
13
0
0
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
32
19
63
50
7
7
19
7
0
0
0
13
% Q
% Arg:
7
0
82
0
0
0
0
7
0
0
0
0
32
0
0
% R
% Ser:
0
7
0
0
0
7
0
0
0
7
0
0
0
38
0
% S
% Thr:
0
50
0
0
0
0
0
32
0
0
0
7
0
7
7
% T
% Val:
7
0
0
7
13
0
0
0
0
0
7
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _