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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNRC6A All Species: 5.76
Human Site: T636 Identified Species: 15.83
UniProt: Q8NDV7 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NDV7 NP_055309.2 1962 210272 T636 S A N G N G K T F T N G W K S
Chimpanzee Pan troglodytes XP_510885 2108 226554 T638 S A N G N G K T F T N G W K S
Rhesus Macaque Macaca mulatta XP_001098210 1937 207379 K611 S A N G N G K K F T N G W K S
Dog Lupus familis XP_547086 1708 181956 T415 V W A K T G G T V E S E G S T
Cat Felis silvestris
Mouse Mus musculus Q3UHK8 1896 203203 G585 N S G G S R R G W E S P A Q N
Rat Rattus norvegicus NP_001101019 1954 209814 K611 S A N G N G S K K L T N G W K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505551 1935 205191 W612 S R K F T N G W K P T D E D D
Chicken Gallus gallus XP_414871 1906 203316 K582 S V N G N T R K F T N G W K S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689365 1881 197727 R581 Q Q L N S W V R G P N A P A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.6 95.1 84.6 N.A. 91.7 93 N.A. 80.4 80.3 N.A. 32.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 89.3 95.7 85.8 N.A. 94.2 95.8 N.A. 87.2 87.5 N.A. 46.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 13.3 N.A. 6.6 40 N.A. 6.6 73.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 26.6 N.A. 60 40 N.A. 6.6 80 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 45 12 0 0 0 0 0 0 0 0 12 12 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 12 0 12 12 % D
% Glu: 0 0 0 0 0 0 0 0 0 23 0 12 12 0 0 % E
% Phe: 0 0 0 12 0 0 0 0 45 0 0 0 0 0 0 % F
% Gly: 0 0 12 67 0 56 23 12 12 0 0 45 23 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 12 12 0 0 34 34 23 0 0 0 0 45 12 % K
% Leu: 0 0 12 0 0 0 0 0 0 12 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 56 12 56 12 0 0 0 0 56 12 0 0 12 % N
% Pro: 0 0 0 0 0 0 0 0 0 23 0 12 12 0 0 % P
% Gln: 12 12 0 0 0 0 0 0 0 0 0 0 0 12 0 % Q
% Arg: 0 12 0 0 0 12 23 12 0 0 0 0 0 0 0 % R
% Ser: 67 12 0 0 23 0 12 0 0 0 23 0 0 12 56 % S
% Thr: 0 0 0 0 23 12 0 34 0 45 23 0 0 0 12 % T
% Val: 12 12 0 0 0 0 12 0 12 0 0 0 0 0 0 % V
% Trp: 0 12 0 0 0 12 0 12 12 0 0 0 45 12 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _