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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHC3 All Species: 15.76
Human Site: S274 Identified Species: 38.52
UniProt: Q8NDX5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NDX5 NP_079223 983 106162 S274 N K K G E S P S L E S R S T A
Chimpanzee Pan troglodytes XP_516870 995 107498 S286 N K K G E S P S L E S R S T A
Rhesus Macaque Macaca mulatta XP_001090096 991 107036 S282 N K K G E S P S L E S R S T A
Dog Lupus familis XP_545282 995 107492 S286 N K K G E S P S L E S R S T A
Cat Felis silvestris
Mouse Mus musculus Q8CHP6 981 105420 L272 K K G G S P G L E S R S T A V
Rat Rattus norvegicus NP_001101132 830 89858 H167 S P P P K V S H H Q L I L Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517932 400 42237
Chicken Gallus gallus XP_426714 1038 111270 E323 K G D S P T P E C R S T P V T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q8QHL5 827 88661 V164 V C I G Q Q A V L L G N S S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P39769 1589 167263 T288 S Q Q Q Q H S T A I S T M S P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 98.1 96.4 N.A. 93.2 79.4 N.A. 35.6 69 N.A. 35.2 N.A. 21 N.A. N.A. N.A.
Protein Similarity: 100 98.5 98.3 97.3 N.A. 96.4 81.7 N.A. 37.9 79.2 N.A. 49.1 N.A. 33.7 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 13.3 0 N.A. 0 13.3 N.A. 20 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 20 20 N.A. 0 20 N.A. 33.3 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 10 0 0 0 0 10 40 % A
% Cys: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 40 0 0 10 10 40 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 60 0 0 10 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 10 0 10 10 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 10 0 10 0 0 0 % I
% Lys: 20 50 40 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 10 50 10 10 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 40 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 10 10 10 10 10 50 0 0 0 0 0 10 0 10 % P
% Gln: 0 10 10 10 20 10 0 0 0 10 0 0 0 10 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 10 40 0 0 0 % R
% Ser: 20 0 0 10 10 40 20 40 0 10 60 10 50 20 0 % S
% Thr: 0 0 0 0 0 10 0 10 0 0 0 20 10 40 20 % T
% Val: 10 0 0 0 0 10 0 10 0 0 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _