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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BHLHE23
All Species:
31.82
Human Site:
S134
Identified Species:
63.64
UniProt:
Q8NDY6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDY6
NP_542173.1
225
23665
S134
I
P
Y
A
H
S
P
S
V
R
K
L
S
K
I
Chimpanzee
Pan troglodytes
Q5IS79
356
38366
N193
N
V
I
P
S
F
N
N
D
K
K
L
S
K
Y
Rhesus Macaque
Macaca mulatta
XP_001092364
380
36853
S275
I
P
Y
A
H
S
P
S
V
R
K
L
S
K
I
Dog
Lupus familis
XP_543092
147
16061
Q79
N
Y
I
L
M
Q
A
Q
A
L
D
E
M
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGW3
223
23682
S132
I
P
Y
A
H
S
P
S
V
R
K
L
S
K
I
Rat
Rattus norvegicus
Q9WUQ3
261
27220
P134
A
A
H
C
Q
G
A
P
G
R
K
L
S
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505951
240
24868
S150
I
P
Y
A
H
S
P
S
V
R
K
L
S
K
I
Chicken
Gallus gallus
Q71T09
311
31525
S205
I
P
Y
A
H
S
P
S
V
R
K
L
S
K
I
Frog
Xenopus laevis
Q91616
352
39643
K134
K
V
V
P
C
Y
S
K
T
Q
K
L
S
K
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523592
232
24054
S162
I
P
Y
A
H
S
P
S
V
R
K
L
S
K
I
Honey Bee
Apis mellifera
XP_001122321
276
29857
S180
I
P
Y
A
H
S
P
S
V
R
K
L
S
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185102
297
33212
S163
I
P
Y
A
H
S
P
S
V
R
K
L
S
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.3
36.3
60.8
N.A.
84.4
31.4
N.A.
64.5
44
21.3
N.A.
N.A.
39.6
34.7
N.A.
32.6
Protein Similarity:
100
30.8
45
62.2
N.A.
88
41.3
N.A.
72.5
50.7
31.2
N.A.
N.A.
53.4
45.6
N.A.
44.1
P-Site Identity:
100
26.6
100
0
N.A.
100
40
N.A.
100
100
33.3
N.A.
N.A.
100
100
N.A.
100
P-Site Similarity:
100
40
100
6.6
N.A.
100
46.6
N.A.
100
100
40
N.A.
N.A.
100
100
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
67
0
0
17
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
9
0
67
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
0
17
0
0
0
0
0
0
0
0
0
0
0
84
% I
% Lys:
9
0
0
0
0
0
0
9
0
9
92
0
0
92
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
9
0
92
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
17
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% N
% Pro:
0
67
0
17
0
0
67
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
9
0
9
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
75
0
0
0
9
9
% R
% Ser:
0
0
0
0
9
67
9
67
0
0
0
0
92
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
0
17
9
0
0
0
0
0
67
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
67
0
0
9
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _