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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BHLHE23 All Species: 43.64
Human Site: T143 Identified Species: 87.27
UniProt: Q8NDY6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NDY6 NP_542173.1 225 23665 T143 R K L S K I A T L L L A K N Y
Chimpanzee Pan troglodytes Q5IS79 356 38366 T202 K K L S K Y E T L Q M A Q I Y
Rhesus Macaque Macaca mulatta XP_001092364 380 36853 T284 R K L S K I A T L L L A K N Y
Dog Lupus familis XP_543092 147 16061 V88 L D E M R R L V A Y L N Q G Q
Cat Felis silvestris
Mouse Mus musculus Q8BGW3 223 23682 T141 R K L S K I A T L L L A K N Y
Rat Rattus norvegicus Q9WUQ3 261 27220 T143 R K L S K I A T L L L A R N Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505951 240 24868 T159 R K L S K I A T L L L A K N Y
Chicken Gallus gallus Q71T09 311 31525 T214 R K L S K I A T L L L A K N Y
Frog Xenopus laevis Q91616 352 39643 T143 Q K L S K I E T L R L A K N Y
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523592 232 24054 T171 R K L S K I A T L L L A K N Y
Honey Bee Apis mellifera XP_001122321 276 29857 T189 R K L S K I A T L L L A K N Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001185102 297 33212 T172 R K L S K I A T L L L A K N Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.3 36.3 60.8 N.A. 84.4 31.4 N.A. 64.5 44 21.3 N.A. N.A. 39.6 34.7 N.A. 32.6
Protein Similarity: 100 30.8 45 62.2 N.A. 88 41.3 N.A. 72.5 50.7 31.2 N.A. N.A. 53.4 45.6 N.A. 44.1
P-Site Identity: 100 53.3 100 6.6 N.A. 100 93.3 N.A. 100 100 80 N.A. N.A. 100 100 N.A. 100
P-Site Similarity: 100 73.3 100 20 N.A. 100 100 N.A. 100 100 86.6 N.A. N.A. 100 100 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 75 0 9 0 0 92 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 9 0 0 0 17 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 84 0 0 0 0 0 0 0 9 0 % I
% Lys: 9 92 0 0 92 0 0 0 0 0 0 0 75 0 0 % K
% Leu: 9 0 92 0 0 0 9 0 92 75 92 0 0 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 84 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 0 0 0 0 0 0 0 9 0 0 17 0 9 % Q
% Arg: 75 0 0 0 9 9 0 0 0 9 0 0 9 0 0 % R
% Ser: 0 0 0 92 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 92 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 92 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _