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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM161B
All Species:
8.48
Human Site:
T409
Identified Species:
20.74
UniProt:
Q8NDZ6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDZ6
NP_699185.1
487
55482
T409
I
Y
P
E
S
I
S
T
L
P
V
D
N
S
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085736
487
55387
T409
I
Y
P
E
S
I
S
T
L
P
A
D
N
S
L
Dog
Lupus familis
XP_546033
504
57283
T426
I
Y
P
E
S
S
S
T
L
P
V
D
N
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C2L6
487
55448
P409
I
Y
P
E
A
A
F
P
L
P
V
D
N
N
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510784
595
67311
D517
I
Y
P
E
P
S
S
D
S
P
M
E
V
N
P
Chicken
Gallus gallus
XP_424528
541
61371
N463
I
Y
P
E
L
N
S
N
T
P
V
E
N
S
L
Frog
Xenopus laevis
Q6GMB1
489
56176
P411
P
E
P
P
G
F
S
P
V
V
D
S
S
P
V
Zebra Danio
Brachydanio rerio
Q7SY10
484
54668
D406
H
S
W
V
I
Y
S
D
E
S
L
P
C
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394096
490
56055
P410
G
L
L
K
A
P
S
P
E
E
C
P
A
D
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790739
517
58155
N422
V
F
D
H
F
Q
S
N
A
T
N
A
S
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
94.4
N.A.
95
N.A.
N.A.
75.6
81.1
53.1
76.5
N.A.
N.A.
42.8
N.A.
44.1
Protein Similarity:
100
N.A.
99.5
95.6
N.A.
97.7
N.A.
N.A.
79.6
86.5
73.2
87.6
N.A.
N.A.
65
N.A.
66.3
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
66.6
N.A.
N.A.
40
66.6
13.3
6.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
80
N.A.
N.A.
60
73.3
33.3
13.3
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
10
0
0
10
0
10
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% C
% Asp:
0
0
10
0
0
0
0
20
0
0
10
40
0
10
0
% D
% Glu:
0
10
0
60
0
0
0
0
20
10
0
20
0
0
0
% E
% Phe:
0
10
0
0
10
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
60
0
0
0
10
20
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
10
0
10
0
0
0
40
0
10
0
0
10
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
20
0
0
10
0
50
20
0
% N
% Pro:
10
0
70
10
10
10
0
30
0
60
0
20
0
10
10
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
30
20
90
0
10
10
0
10
20
30
10
% S
% Thr:
0
0
0
0
0
0
0
30
10
10
0
0
0
10
10
% T
% Val:
10
0
0
10
0
0
0
0
10
10
40
0
10
0
10
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
60
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _