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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM161B
All Species:
19.7
Human Site:
Y403
Identified Species:
48.15
UniProt:
Q8NDZ6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDZ6
NP_699185.1
487
55482
Y403
G
N
H
S
W
G
I
Y
P
E
S
I
S
T
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085736
487
55387
Y403
G
N
H
S
W
G
I
Y
P
E
S
I
S
T
L
Dog
Lupus familis
XP_546033
504
57283
Y420
G
N
H
S
W
G
I
Y
P
E
S
S
S
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C2L6
487
55448
Y403
G
N
H
S
W
G
I
Y
P
E
A
A
F
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510784
595
67311
Y511
G
N
H
S
W
G
I
Y
P
E
P
S
S
D
S
Chicken
Gallus gallus
XP_424528
541
61371
Y457
G
N
Y
S
W
G
I
Y
P
E
L
N
S
N
T
Frog
Xenopus laevis
Q6GMB1
489
56176
E405
Y
S
W
G
L
Y
P
E
P
P
G
F
S
P
V
Zebra Danio
Brachydanio rerio
Q7SY10
484
54668
S400
L
K
T
L
G
G
H
S
W
V
I
Y
S
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394096
490
56055
L404
G
G
Y
T
W
E
G
L
L
K
A
P
S
P
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790739
517
58155
F416
A
G
Y
S
Y
G
V
F
D
H
F
Q
S
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
94.4
N.A.
95
N.A.
N.A.
75.6
81.1
53.1
76.5
N.A.
N.A.
42.8
N.A.
44.1
Protein Similarity:
100
N.A.
99.5
95.6
N.A.
97.7
N.A.
N.A.
79.6
86.5
73.2
87.6
N.A.
N.A.
65
N.A.
66.3
P-Site Identity:
100
N.A.
100
93.3
N.A.
73.3
N.A.
N.A.
73.3
66.6
13.3
13.3
N.A.
N.A.
20
N.A.
20
P-Site Similarity:
100
N.A.
100
93.3
N.A.
80
N.A.
N.A.
73.3
73.3
26.6
13.3
N.A.
N.A.
46.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
20
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
20
0
% D
% Glu:
0
0
0
0
0
10
0
10
0
60
0
0
0
0
20
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
10
10
0
0
% F
% Gly:
70
20
0
10
10
80
10
0
0
0
10
0
0
0
0
% G
% His:
0
0
50
0
0
0
10
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
60
0
0
0
10
20
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
10
0
0
10
10
0
0
10
10
0
10
0
0
0
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
60
0
0
0
0
0
0
0
0
0
10
0
20
0
% N
% Pro:
0
0
0
0
0
0
10
0
70
10
10
10
0
30
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
70
0
0
0
10
0
0
30
20
90
0
10
% S
% Thr:
0
0
10
10
0
0
0
0
0
0
0
0
0
30
10
% T
% Val:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
10
0
70
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
10
0
30
0
10
10
0
60
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _