KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM104
All Species:
27.27
Human Site:
S271
Identified Species:
50
UniProt:
Q8NE00
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NE00
NP_060198.3
496
55679
S271
H
P
P
L
A
D
F
S
G
V
R
N
L
F
G
Chimpanzee
Pan troglodytes
XP_523714
496
55145
S271
H
P
P
L
A
D
F
S
G
V
R
N
L
F
G
Rhesus Macaque
Macaca mulatta
XP_001089622
496
55721
S271
H
P
P
L
A
D
F
S
G
V
R
N
L
F
G
Dog
Lupus familis
XP_540420
495
55718
S270
H
P
P
L
A
D
L
S
G
V
R
N
L
F
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3TB48
496
55820
L271
H
P
P
L
A
N
F
L
G
V
Q
N
L
F
G
Rat
Rattus norvegicus
XP_221104
496
55610
L271
H
P
P
L
A
N
F
L
G
V
Q
N
L
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513737
503
55788
S278
H
P
P
L
A
E
L
S
G
V
R
N
L
F
G
Chicken
Gallus gallus
Q5F3I6
497
56100
S272
H
P
S
M
A
Q
L
S
G
I
R
N
L
F
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693756
493
55194
S267
K
P
S
V
A
Q
I
S
G
V
P
N
L
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPF8
509
57548
Y283
H
P
A
T
F
N
V
Y
G
I
P
S
L
F
G
Honey Bee
Apis mellifera
XP_624947
517
58006
M281
N
P
P
A
A
N
I
M
G
I
P
S
L
F
G
Nematode Worm
Caenorhab. elegans
Q17598
492
54003
A276
D
N
V
F
G
K
I
A
L
V
Y
G
V
V
G
Sea Urchin
Strong. purpuratus
XP_780904
427
48681
Y212
N
F
F
G
V
C
V
Y
A
F
M
C
H
H
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.5
98.5
92.7
N.A.
89.7
89.1
N.A.
80.7
81.8
N.A.
73.9
N.A.
43
47
38.3
43.5
Protein Similarity:
100
92.5
99.4
96.1
N.A.
94.1
93.9
N.A.
88.6
90.5
N.A.
82.6
N.A.
64.8
64.9
57.8
59.6
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
86.6
66.6
N.A.
60
N.A.
40
46.6
13.3
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
80
N.A.
66.6
N.A.
60
73.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
77
0
0
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
0
0
0
0
31
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
8
8
8
0
39
0
0
8
0
0
0
85
0
% F
% Gly:
0
0
0
8
8
0
0
0
85
0
0
8
0
0
93
% G
% His:
70
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
0
0
0
0
0
0
24
0
0
24
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
54
0
0
24
16
8
0
0
0
85
0
0
% L
% Met:
0
0
0
8
0
0
0
8
0
0
8
0
0
0
0
% M
% Asn:
16
8
0
0
0
31
0
0
0
0
0
70
0
0
0
% N
% Pro:
0
85
62
0
0
0
0
0
0
0
24
0
0
0
0
% P
% Gln:
0
0
0
0
0
16
0
0
0
0
16
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% R
% Ser:
0
0
16
0
0
0
0
54
0
0
0
16
0
0
8
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
8
8
0
16
0
0
70
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
16
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _