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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS22
All Species:
13.03
Human Site:
T217
Identified Species:
71.67
UniProt:
Q8NE09
Number Species:
4
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NE09
NP_056483.3
1264
147163
T217
L
A
K
Q
S
Q
Q
T
V
S
T
F
S
L
P
Chimpanzee
Pan troglodytes
XP_519883
1262
146794
T215
L
A
K
Q
S
Q
Q
T
V
S
T
F
S
L
P
Rhesus Macaque
Macaca mulatta
XP_001096690
1265
146984
T217
L
A
K
Q
S
Q
Q
T
V
S
T
F
S
L
P
Dog
Lupus familis
XP_532281
1262
147508
T201
L
A
K
Q
S
L
Q
T
V
P
T
F
S
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506363
1077
124682
G153
S
L
G
I
A
K
S
G
V
M
S
S
P
Q
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
96.7
81.1
N.A.
N.A.
N.A.
N.A.
54.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
97.8
88.8
N.A.
N.A.
N.A.
N.A.
67.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
80
0
0
20
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% F
% Gly:
0
0
20
0
0
0
0
20
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
80
0
0
20
0
0
0
0
0
0
0
0
0
% K
% Leu:
80
20
0
0
0
20
0
0
0
0
0
0
0
80
0
% L
% Met:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
20
0
0
20
0
80
% P
% Gln:
0
0
0
80
0
60
80
0
0
0
0
0
0
20
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
0
0
0
80
0
20
0
0
60
20
20
80
0
20
% S
% Thr:
0
0
0
0
0
0
0
80
0
0
80
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _