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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C5orf35
All Species:
22.12
Human Site:
Y259
Identified Species:
81.11
UniProt:
Q8NE22
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NE22
NP_714917.1
299
34095
Y259
F
P
I
E
L
K
Q
Y
L
P
N
I
A
Y
S
Chimpanzee
Pan troglodytes
XP_517753
299
34091
Y259
F
P
I
E
L
K
Q
Y
L
P
N
I
A
Y
S
Rhesus Macaque
Macaca mulatta
XP_001101150
299
33951
Y259
F
P
V
E
L
K
Q
Y
L
P
N
I
A
Y
S
Dog
Lupus familis
XP_849744
299
34249
Y259
F
P
I
E
L
K
Q
Y
L
P
N
I
A
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507930
317
34549
Y277
F
P
I
E
F
K
R
Y
L
P
N
I
A
Y
S
Chicken
Gallus gallus
XP_001233556
291
32100
Y251
F
P
V
E
L
K
Q
Y
L
P
N
I
V
Y
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788396
120
13285
R87
I
Y
R
S
C
A
R
R
D
R
L
G
P
Y
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.6
92.6
N.A.
N.A.
N.A.
N.A.
64.9
58.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
25.7
Protein Similarity:
100
100
99.6
96.6
N.A.
N.A.
N.A.
N.A.
75.7
73.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
31.4
P-Site Identity:
100
100
93.3
100
N.A.
N.A.
N.A.
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
N.A.
N.A.
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
0
0
0
0
0
0
72
0
0
% A
% Cys:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% D
% Glu:
0
0
0
86
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
86
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
58
0
0
0
0
0
0
0
0
86
0
0
0
% I
% Lys:
0
0
0
0
0
86
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
72
0
0
0
86
0
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
86
0
0
0
0
% N
% Pro:
0
86
0
0
0
0
0
0
0
86
0
0
15
0
0
% P
% Gln:
0
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
15
0
0
0
29
15
0
15
0
0
0
0
0
% R
% Ser:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
86
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
29
0
0
0
0
0
0
0
0
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
0
0
0
86
0
0
0
0
0
100
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _