KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHDH
All Species:
26.06
Human Site:
S354
Identified Species:
71.67
UniProt:
Q8NE62
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NE62
NP_060867.2
594
65358
S354
T
R
P
I
T
L
H
S
A
Q
K
P
L
R
K
Chimpanzee
Pan troglodytes
XP_516532
594
65325
S354
T
R
P
I
T
L
H
S
A
Q
K
P
L
R
K
Rhesus Macaque
Macaca mulatta
XP_001082768
594
65259
S354
T
H
P
I
T
L
H
S
A
Q
K
P
L
Q
K
Dog
Lupus familis
XP_541839
575
63188
S335
T
L
P
I
T
L
H
S
A
Q
K
P
L
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ64
596
66396
S356
T
Q
P
I
T
L
H
S
A
Q
K
P
L
R
K
Rat
Rattus norvegicus
NP_942026
599
66370
S359
T
Q
P
I
T
L
H
S
A
Q
K
P
L
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414335
716
79948
S476
T
K
P
I
T
L
Y
S
A
Q
K
P
V
N
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495846
599
67246
N360
T
Q
P
V
T
L
Y
N
K
S
S
W
K
F
P
Sea Urchin
Strong. purpuratus
XP_792493
605
67098
K352
K
K
P
I
T
L
Y
K
A
Q
W
K
F
P
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.8
85
N.A.
82.8
84.6
N.A.
N.A.
64.9
N.A.
N.A.
N.A.
N.A.
N.A.
53.4
59.5
Protein Similarity:
100
99.4
98.4
90.2
N.A.
89.9
90.6
N.A.
N.A.
73
N.A.
N.A.
N.A.
N.A.
N.A.
69.4
71.7
P-Site Identity:
100
100
86.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
40
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
100
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
89
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
12
0
0
0
0
67
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
89
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
23
0
0
0
0
0
12
12
0
78
12
12
0
67
% K
% Leu:
0
12
0
0
0
100
0
0
0
0
0
0
67
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% N
% Pro:
0
0
100
0
0
0
0
0
0
0
0
78
0
12
12
% P
% Gln:
0
34
0
0
0
0
0
0
0
89
0
0
0
12
0
% Q
% Arg:
0
23
0
0
0
0
0
0
0
0
0
0
0
56
0
% R
% Ser:
0
0
0
0
0
0
0
78
0
12
12
0
0
0
0
% S
% Thr:
89
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
0
% W
% Tyr:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _