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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHDH
All Species:
28.48
Human Site:
T194
Identified Species:
78.33
UniProt:
Q8NE62
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NE62
NP_060867.2
594
65358
T194
L
R
V
S
R
G
K
T
N
H
P
L
H
C
A
Chimpanzee
Pan troglodytes
XP_516532
594
65325
T194
L
R
V
S
R
G
K
T
N
H
P
L
H
C
A
Rhesus Macaque
Macaca mulatta
XP_001082768
594
65259
T194
L
R
V
S
R
G
K
T
N
H
P
L
H
C
A
Dog
Lupus familis
XP_541839
575
63188
T175
L
H
V
S
R
G
R
T
D
H
P
L
H
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ64
596
66396
T196
L
H
V
S
R
G
K
T
N
H
P
L
H
Q
A
Rat
Rattus norvegicus
NP_942026
599
66370
T199
L
H
V
S
R
G
K
T
N
H
P
L
H
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414335
716
79948
T316
L
Y
V
S
R
G
K
T
N
H
P
L
H
Q
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495846
599
67246
K186
N
G
P
L
Y
V
K
K
G
D
A
E
N
P
L
Sea Urchin
Strong. purpuratus
XP_792493
605
67098
S190
L
H
V
S
R
G
K
S
N
N
P
L
F
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.8
85
N.A.
82.8
84.6
N.A.
N.A.
64.9
N.A.
N.A.
N.A.
N.A.
N.A.
53.4
59.5
Protein Similarity:
100
99.4
98.4
90.2
N.A.
89.9
90.6
N.A.
N.A.
73
N.A.
N.A.
N.A.
N.A.
N.A.
69.4
71.7
P-Site Identity:
100
100
100
73.3
N.A.
86.6
86.6
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
66.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
89
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% C
% Asp:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
12
0
0
0
89
0
0
12
0
0
0
0
0
0
% G
% His:
0
45
0
0
0
0
0
0
0
78
0
0
78
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
89
12
0
0
0
0
0
0
0
% K
% Leu:
89
0
0
12
0
0
0
0
0
0
0
89
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
78
12
0
0
12
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
89
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% Q
% Arg:
0
34
0
0
89
0
12
0
0
0
0
0
0
12
0
% R
% Ser:
0
0
0
89
0
0
0
12
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
78
0
0
0
0
0
0
0
% T
% Val:
0
0
89
0
0
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _