KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHDH
All Species:
21.52
Human Site:
Y287
Identified Species:
59.17
UniProt:
Q8NE62
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NE62
NP_060867.2
594
65358
Y287
N
G
Q
S
H
R
A
Y
A
S
K
E
V
I
L
Chimpanzee
Pan troglodytes
XP_516532
594
65325
Y287
N
G
Q
S
H
R
A
Y
A
S
K
E
V
I
L
Rhesus Macaque
Macaca mulatta
XP_001082768
594
65259
Y287
N
G
Q
S
H
R
A
Y
A
S
K
E
V
I
L
Dog
Lupus familis
XP_541839
575
63188
Y268
N
G
Q
T
R
R
A
Y
A
S
K
E
V
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ64
596
66396
Y289
D
G
Q
R
H
K
A
Y
V
S
R
E
V
I
L
Rat
Rattus norvegicus
NP_942026
599
66370
Y292
D
G
Q
S
H
K
A
Y
V
S
R
E
V
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414335
716
79948
F409
N
G
Q
T
E
K
A
F
A
S
K
E
V
I
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495846
599
67246
D282
K
L
N
F
V
G
T
D
S
I
D
S
Y
S
R
Sea Urchin
Strong. purpuratus
XP_792493
605
67098
R285
N
K
A
K
K
V
A
R
A
T
K
D
V
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.8
85
N.A.
82.8
84.6
N.A.
N.A.
64.9
N.A.
N.A.
N.A.
N.A.
N.A.
53.4
59.5
Protein Similarity:
100
99.4
98.4
90.2
N.A.
89.9
90.6
N.A.
N.A.
73
N.A.
N.A.
N.A.
N.A.
N.A.
69.4
71.7
P-Site Identity:
100
100
100
86.6
N.A.
66.6
73.3
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
89
0
67
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
23
0
0
0
0
0
0
12
0
0
12
12
0
0
0
% D
% Glu:
0
0
0
0
12
0
0
0
0
0
0
78
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
78
0
0
0
12
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
56
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
89
0
% I
% Lys:
12
12
0
12
12
34
0
0
0
0
67
0
0
0
0
% K
% Leu:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
89
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
67
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
78
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
12
45
0
12
0
0
23
0
0
0
12
% R
% Ser:
0
0
0
45
0
0
0
0
12
78
0
12
0
12
0
% S
% Thr:
0
0
0
23
0
0
12
0
0
12
0
0
0
0
0
% T
% Val:
0
0
0
0
12
12
0
0
23
0
0
0
89
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _