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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHDH
All Species:
32.73
Human Site:
Y452
Identified Species:
90
UniProt:
Q8NE62
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NE62
NP_060867.2
594
65358
Y452
H
P
V
I
Q
P
N
Y
L
S
T
E
T
D
I
Chimpanzee
Pan troglodytes
XP_516532
594
65325
Y452
H
P
V
I
Q
P
N
Y
L
S
T
E
T
D
I
Rhesus Macaque
Macaca mulatta
XP_001082768
594
65259
Y452
H
P
V
I
Q
P
N
Y
L
S
T
E
T
D
I
Dog
Lupus familis
XP_541839
575
63188
Y433
H
P
V
I
Q
P
N
Y
L
S
T
E
T
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ64
596
66396
Y454
H
P
V
I
H
P
N
Y
L
S
T
E
T
D
V
Rat
Rattus norvegicus
NP_942026
599
66370
Y457
H
P
M
I
N
P
N
Y
L
S
T
E
T
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414335
716
79948
Y574
H
P
I
I
E
P
N
Y
M
S
A
E
R
D
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_495846
599
67246
Y461
A
P
I
I
N
P
N
Y
M
E
E
D
S
D
W
Sea Urchin
Strong. purpuratus
XP_792493
605
67098
Y452
H
P
I
L
D
P
N
Y
L
A
T
E
D
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.8
85
N.A.
82.8
84.6
N.A.
N.A.
64.9
N.A.
N.A.
N.A.
N.A.
N.A.
53.4
59.5
Protein Similarity:
100
99.4
98.4
90.2
N.A.
89.9
90.6
N.A.
N.A.
73
N.A.
N.A.
N.A.
N.A.
N.A.
69.4
71.7
P-Site Identity:
100
100
100
100
N.A.
86.6
80
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
40
60
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
0
0
0
0
12
12
100
0
% D
% Glu:
0
0
0
0
12
0
0
0
0
12
12
89
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
89
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
34
89
0
0
0
0
0
0
0
0
0
0
56
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
12
0
0
0
0
78
0
0
0
0
0
0
% L
% Met:
0
0
12
0
0
0
0
0
23
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
23
0
100
0
0
0
0
0
0
0
0
% N
% Pro:
0
100
0
0
0
100
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
45
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% R
% Ser:
0
0
0
0
0
0
0
0
0
78
0
0
12
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
78
0
67
0
0
% T
% Val:
0
0
56
0
0
0
0
0
0
0
0
0
0
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _