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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIPK4
All Species:
12.73
Human Site:
T552
Identified Species:
40
UniProt:
Q8NE63
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NE63
NP_653286.2
616
69425
T552
G
P
N
I
D
N
M
T
M
E
A
E
R
P
D
Chimpanzee
Pan troglodytes
XP_524269
616
69492
T552
G
P
N
I
D
N
M
T
M
E
A
Q
R
P
D
Rhesus Macaque
Macaca mulatta
XP_001096200
616
69596
T552
G
P
N
I
D
N
M
T
M
E
A
E
R
P
D
Dog
Lupus familis
XP_533668
615
68775
T552
G
P
D
I
K
D
M
T
M
D
A
D
G
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3V016
616
69260
P553
G
P
G
I
K
D
R
P
M
D
A
E
R
P
G
Rat
Rattus norvegicus
Q4V793
616
69279
P553
G
P
S
I
K
D
R
P
M
D
A
E
R
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515712
443
49440
E380
L
E
L
E
L
E
L
E
A
E
R
P
G
P
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073629
1226
133548
G979
T
N
G
P
N
A
N
G
Y
D
S
K
G
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
97.4
89.4
N.A.
87.1
86.5
N.A.
47.8
N.A.
N.A.
23.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
98
91.7
N.A.
90
89.9
N.A.
53.7
N.A.
N.A.
34.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
53.3
N.A.
53.3
46.6
N.A.
13.3
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
66.6
66.6
N.A.
26.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
0
0
13
0
75
0
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
38
38
0
0
0
50
0
13
0
0
38
% D
% Glu:
0
13
0
13
0
13
0
13
0
50
0
50
0
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
75
0
25
0
0
0
0
13
0
0
0
0
38
0
38
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
38
0
0
0
0
0
0
13
0
0
0
% K
% Leu:
13
0
13
0
13
0
13
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
50
0
75
0
0
0
0
0
0
% M
% Asn:
0
13
38
0
13
38
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
75
0
13
0
0
0
25
0
0
0
13
0
75
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Q
% Arg:
0
0
0
0
0
0
25
0
0
0
13
0
63
0
0
% R
% Ser:
0
0
13
0
0
0
0
0
0
0
13
0
0
13
0
% S
% Thr:
13
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _