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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BVES All Species: 26.67
Human Site: S318 Identified Species: 58.67
UniProt: Q8NE79 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NE79 NP_009004.2 360 41451 S318 R G T S S M S S L H V S S P H
Chimpanzee Pan troglodytes XP_527578 360 41356 S318 R G T S S M S S L H V S S P H
Rhesus Macaque Macaca mulatta XP_001087113 360 41399 S318 R G T S S M S S L H V S S P H
Dog Lupus familis XP_539065 620 71224 S578 R G T S S M S S L H V P S P H
Cat Felis silvestris
Mouse Mus musculus Q9ES83 358 40997 S318 R G S S S T A S L P M S S P Q
Rat Rattus norvegicus NP_001071058 356 40842 S318 R G S S S T A S L P M S S P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505932 353 40633 S313 R G T P T A P S L R V S S P Y
Chicken Gallus gallus Q9DG25 305 34957 T270 R L P N F Y H T S L P E T P P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001001847 316 36296 Q281 C S Q L S M M Q M R N S M A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393861 360 40374 S306 L S S D N G I S N L K D R P A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190580 363 40758 G319 V I H R T S A G D D R P I G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.8 55.8 N.A. 87.2 84.4 N.A. 75.8 29.4 N.A. 59.4 N.A. N.A. 31.9 N.A. 29.4
Protein Similarity: 100 99.7 99.7 56.7 N.A. 92.7 91.6 N.A. 87.7 46.9 N.A. 74.4 N.A. N.A. 52.2 N.A. 48.2
P-Site Identity: 100 100 100 93.3 N.A. 60 60 N.A. 60 13.3 N.A. 20 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 80 80 N.A. 73.3 33.3 N.A. 26.6 N.A. N.A. 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 28 0 0 0 0 0 0 10 10 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 10 10 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 64 0 0 0 10 0 10 0 0 0 0 0 10 0 % G
% His: 0 0 10 0 0 0 10 0 0 37 0 0 0 0 37 % H
% Ile: 0 10 0 0 0 0 10 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 10 10 0 10 0 0 0 0 64 19 0 0 0 0 0 % L
% Met: 0 0 0 0 0 46 10 0 10 0 19 0 10 0 0 % M
% Asn: 0 0 0 10 10 0 0 0 10 0 10 0 0 0 0 % N
% Pro: 0 0 10 10 0 0 10 0 0 19 10 19 0 82 10 % P
% Gln: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 19 % Q
% Arg: 73 0 0 10 0 0 0 0 0 19 10 0 10 0 10 % R
% Ser: 0 19 28 55 64 10 37 73 10 0 0 64 64 0 10 % S
% Thr: 0 0 46 0 19 19 0 10 0 0 0 0 10 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 46 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _