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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GLIS3 All Species: 16.97
Human Site: S424 Identified Species: 46.67
UniProt: Q8NEA6 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NEA6 NP_001035878.1 775 83667 S424 E G C E K A F S R L E N L K I
Chimpanzee Pan troglodytes Q5IS56 1580 169881 S558 E G C T K A Y S R L E N L K T
Rhesus Macaque Macaca mulatta XP_001083553 907 97858 S556 E G C K K A F S R L E N L K I
Dog Lupus familis XP_541295 826 88622 S474 E G C K K A F S R L E N L K I
Cat Felis silvestris
Mouse Mus musculus Q6XP49 780 83863 L429 A F S R L E N L K I H L R S H
Rat Rattus norvegicus Q5XIU2 638 68981 F288 G Y G L K S H F R T H T G E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P55879 663 73088 R313 G C S K A Y S R L E N L K T H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001074076 787 86851 N433 A R K H K P F N A R Y K L L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P19538 1397 153262 S529 E G C F K A Y S R L E N L K T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.3 79.5 83 N.A. 85.3 21.5 N.A. N.A. 26 N.A. 37.6 N.A. 23.5 N.A. N.A. N.A.
Protein Similarity: 100 30.8 82.3 87 N.A. 89.6 35.8 N.A. N.A. 41.4 N.A. 50.3 N.A. 34 N.A. N.A. N.A.
P-Site Identity: 100 80 93.3 93.3 N.A. 0 13.3 N.A. N.A. 0 N.A. 26.6 N.A. 80 N.A. N.A. N.A.
P-Site Similarity: 100 86.6 100 100 N.A. 13.3 26.6 N.A. N.A. 6.6 N.A. 33.3 N.A. 86.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 0 0 0 12 56 0 0 12 0 0 0 0 0 0 % A
% Cys: 0 12 56 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 56 0 0 12 0 12 0 0 0 12 56 0 0 12 0 % E
% Phe: 0 12 0 12 0 0 45 12 0 0 0 0 0 0 0 % F
% Gly: 23 56 12 0 0 0 0 0 0 0 0 0 12 0 0 % G
% His: 0 0 0 12 0 0 12 0 0 0 23 0 0 0 23 % H
% Ile: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 45 % I
% Lys: 0 0 12 34 78 0 0 0 12 0 0 12 12 56 12 % K
% Leu: 0 0 0 12 12 0 0 12 12 56 0 23 67 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 12 12 0 0 12 56 0 0 0 % N
% Pro: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 12 0 12 0 0 0 12 67 12 0 0 12 0 0 % R
% Ser: 0 0 23 0 0 12 12 56 0 0 0 0 0 12 0 % S
% Thr: 0 0 0 12 0 0 0 0 0 12 0 12 0 12 23 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 0 12 23 0 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _