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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GMCL1L
All Species:
23.03
Human Site:
S227
Identified Species:
63.33
UniProt:
Q8NEA9
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEA9
NP_848526
526
60201
S227
V
E
I
Y
G
L
D
S
V
K
K
K
C
L
E
Chimpanzee
Pan troglodytes
XP_001148182
526
59889
S227
V
E
I
Y
G
L
D
S
V
K
K
K
C
L
E
Rhesus Macaque
Macaca mulatta
XP_001095683
523
59780
S224
V
G
T
Y
G
L
D
S
V
K
K
K
C
L
E
Dog
Lupus familis
XP_538534
529
59915
S231
A
G
T
Y
G
L
D
S
V
K
K
K
C
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q920G9
524
59636
S225
A
G
T
Y
G
L
D
S
V
K
K
K
C
L
E
Rat
Rattus norvegicus
NP_001029103
524
59708
S225
A
G
T
Y
G
L
D
S
V
K
K
K
C
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_996933
503
57954
S199
A
T
M
Y
G
L
D
S
V
M
K
K
C
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01820
569
65134
L198
F
Q
W
F
Q
I
N
L
L
S
I
Y
S
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784533
465
52867
L197
F
E
W
L
E
L
N
L
M
V
A
Q
K
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
91.4
86.5
N.A.
84.4
84.9
N.A.
N.A.
N.A.
N.A.
69
N.A.
30.7
N.A.
N.A.
41.2
Protein Similarity:
100
97.7
94.1
90.5
N.A.
89.5
89.9
N.A.
N.A.
N.A.
N.A.
78.5
N.A.
49.2
N.A.
N.A.
57.2
P-Site Identity:
100
100
86.6
80
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
86.6
80
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
80
N.A.
40
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
78
0
0
% C
% Asp:
0
0
0
0
0
0
78
0
0
0
0
0
0
0
0
% D
% Glu:
0
34
0
0
12
0
0
0
0
0
0
0
0
0
78
% E
% Phe:
23
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
45
0
0
78
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
23
0
0
12
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
67
78
78
12
12
0
% K
% Leu:
0
0
0
12
0
89
0
23
12
0
0
0
0
78
0
% L
% Met:
0
0
12
0
0
0
0
0
12
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% P
% Gln:
0
12
0
0
12
0
0
0
0
0
0
12
0
0
12
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
78
0
12
0
0
12
0
0
% S
% Thr:
0
12
45
0
0
0
0
0
0
0
0
0
0
0
12
% T
% Val:
34
0
0
0
0
0
0
0
78
12
0
0
0
0
0
% V
% Trp:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
78
0
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _