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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GMCL1L
All Species:
7.88
Human Site:
S49
Identified Species:
21.67
UniProt:
Q8NEA9
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEA9
NP_848526
526
60201
S49
G
F
C
Y
C
P
G
S
H
K
R
K
R
S
S
Chimpanzee
Pan troglodytes
XP_001148182
526
59889
S49
G
F
C
Y
C
P
G
S
H
K
R
K
R
S
S
Rhesus Macaque
Macaca mulatta
XP_001095683
523
59780
S49
G
F
C
Y
C
P
G
S
H
K
S
S
G
A
F
Dog
Lupus familis
XP_538534
529
59915
G53
G
F
C
Y
C
P
G
G
R
K
R
K
R
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q920G9
524
59636
G47
S
F
C
Y
C
P
G
G
R
K
R
K
R
S
S
Rat
Rattus norvegicus
NP_001029103
524
59708
G47
G
F
C
Y
C
P
G
G
R
K
R
K
R
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_996933
503
57954
D44
R
S
L
R
C
E
C
D
S
E
P
E
E
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01820
569
65134
Q42
P
A
Q
L
D
T
T
Q
P
K
K
K
K
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784533
465
52867
P42
A
N
E
V
L
H
T
P
Q
R
K
K
M
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
91.4
86.5
N.A.
84.4
84.9
N.A.
N.A.
N.A.
N.A.
69
N.A.
30.7
N.A.
N.A.
41.2
Protein Similarity:
100
97.7
94.1
90.5
N.A.
89.5
89.9
N.A.
N.A.
N.A.
N.A.
78.5
N.A.
49.2
N.A.
N.A.
57.2
P-Site Identity:
100
100
66.6
80
N.A.
80
86.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
73.3
80
N.A.
80
86.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% A
% Cys:
0
0
67
0
78
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
12
% D
% Glu:
0
0
12
0
0
12
0
0
0
12
0
12
12
12
0
% E
% Phe:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
56
0
0
0
0
0
67
34
0
0
0
0
12
0
12
% G
% His:
0
0
0
0
0
12
0
0
34
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
78
23
78
12
12
0
% K
% Leu:
0
0
12
12
12
0
0
0
0
0
0
0
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
67
0
12
12
0
12
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
12
12
0
0
0
0
0
0
% Q
% Arg:
12
0
0
12
0
0
0
0
34
12
56
0
56
0
0
% R
% Ser:
12
12
0
0
0
0
0
34
12
0
12
12
0
56
56
% S
% Thr:
0
0
0
0
0
12
23
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _