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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAPDC1B
All Species:
26.67
Human Site:
T195
Identified Species:
41.9
UniProt:
Q8NEB5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEB5
NP_001096029.1
223
25159
T195
R
Q
Y
Y
P
P
L
T
D
A
E
C
H
K
P
Chimpanzee
Pan troglodytes
XP_001170623
223
25141
T195
R
Q
Y
Y
P
P
L
T
D
A
E
C
H
K
P
Rhesus Macaque
Macaca mulatta
XP_001092746
343
37863
T314
R
Q
Y
Y
P
P
L
T
D
A
E
C
H
K
P
Dog
Lupus familis
XP_532804
262
29068
T234
R
Q
Y
Y
P
P
L
T
D
A
E
C
H
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMZ3
260
29204
T232
R
Q
Y
Y
P
P
L
T
D
V
E
C
H
K
P
Rat
Rattus norvegicus
O08564
282
31978
S255
D
F
F
K
T
T
E
S
N
K
E
R
K
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506195
245
27549
Y210
Y
L
C
Y
R
Q
Y
Y
P
P
L
T
D
S
E
Chicken
Gallus gallus
XP_001234075
241
26848
M210
R
Q
Y
Y
P
P
L
M
D
S
V
C
H
K
P
Frog
Xenopus laevis
Q6GQ62
226
25153
V195
R
Q
Y
Y
P
S
L
V
E
R
D
C
H
Q
P
Zebra Danio
Brachydanio rerio
XP_001921179
256
28767
L211
R
Q
H
Y
P
P
F
L
H
I
D
C
H
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623887
268
30640
S237
Y
Y
Y
P
P
L
D
S
Q
V
C
H
K
P
Y
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
S278
T
F
W
T
D
L
F
S
N
N
S
T
E
S
E
Sea Urchin
Strong. purpuratus
XP_787511
258
29394
T217
R
Q
Y
F
P
A
L
T
H
A
T
C
D
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFD1
364
40756
Y298
L
Q
F
F
P
P
P
Y
H
T
E
G
W
G
P
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
D251
R
R
I
F
P
P
I
D
D
P
L
P
F
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
63.8
74.4
N.A.
76.5
20.2
N.A.
68.5
64.3
64.5
51.5
N.A.
N.A.
41.7
22.5
37.9
Protein Similarity:
100
100
64.1
78.2
N.A.
80
35.4
N.A.
77.5
72.1
77.8
67.5
N.A.
N.A.
53.7
36.3
51.9
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
6.6
80
60
46.6
N.A.
N.A.
13.3
0
60
P-Site Similarity:
100
100
100
100
N.A.
93.3
33.3
N.A.
6.6
86.6
80
60
N.A.
N.A.
20
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.5
31.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.1
48.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
34
0
0
0
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
7
60
0
0
0
% C
% Asp:
7
0
0
0
7
0
7
7
47
0
14
0
14
0
7
% D
% Glu:
0
0
0
0
0
0
7
0
7
0
47
0
7
7
14
% E
% Phe:
0
14
14
20
0
0
14
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% G
% His:
0
0
7
0
0
0
0
0
20
0
0
7
54
0
0
% H
% Ile:
0
0
7
0
0
0
7
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
0
7
0
0
0
0
0
7
0
0
14
54
0
% K
% Leu:
7
7
0
0
0
14
54
7
0
0
14
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
14
7
0
0
0
0
0
% N
% Pro:
0
0
0
7
80
60
7
0
7
14
0
7
0
7
60
% P
% Gln:
0
67
0
0
0
7
0
0
7
0
0
0
0
7
0
% Q
% Arg:
67
7
0
0
7
0
0
0
0
7
0
7
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
20
0
7
7
0
0
14
14
% S
% Thr:
7
0
0
7
7
7
0
40
0
7
7
14
0
0
0
% T
% Val:
0
0
0
0
0
0
0
7
0
14
7
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
14
7
60
60
0
0
7
14
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _