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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAPDC1B
All Species:
11.82
Human Site:
T42
Identified Species:
18.57
UniProt:
Q8NEB5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEB5
NP_001096029.1
223
25159
T42
K
F
L
K
K
A
D
T
R
D
S
R
Q
A
C
Chimpanzee
Pan troglodytes
XP_001170623
223
25141
T42
K
F
L
K
K
A
D
T
R
D
S
R
Q
A
C
Rhesus Macaque
Macaca mulatta
XP_001092746
343
37863
T161
K
F
L
K
K
A
D
T
R
D
S
R
Q
A
C
Dog
Lupus familis
XP_532804
262
29068
P81
R
C
L
R
K
A
G
P
T
D
S
R
Q
A
C
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMZ3
260
29204
A79
K
F
L
R
K
A
D
A
T
D
S
K
Q
A
C
Rat
Rattus norvegicus
O08564
282
31978
V102
I
A
T
I
Y
K
A
V
G
A
F
L
F
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506195
245
27549
R57
K
Y
L
K
K
A
D
R
T
D
T
K
Q
A
C
Chicken
Gallus gallus
XP_001234075
241
26848
H57
R
L
F
L
G
A
D
H
E
D
T
R
E
A
S
Frog
Xenopus laevis
Q6GQ62
226
25153
G42
R
L
F
W
K
A
D
G
T
D
S
R
E
A
G
Zebra Danio
Brachydanio rerio
XP_001921179
256
28767
R58
K
I
I
Q
R
T
D
R
T
E
I
K
E
A
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623887
268
30640
K84
V
F
L
V
Y
K
D
K
T
D
I
Y
Q
A
I
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
Y125
L
F
V
R
L
L
T
Y
F
G
Y
S
Q
I
G
Sea Urchin
Strong. purpuratus
XP_787511
258
29394
T64
L
V
P
L
C
V
I
T
I
F
S
L
M
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFD1
364
40756
D145
F
R
R
R
D
V
Y
D
L
H
H
A
V
L
G
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
T98
H
L
I
F
I
L
Y
T
S
L
L
G
L
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
63.8
74.4
N.A.
76.5
20.2
N.A.
68.5
64.3
64.5
51.5
N.A.
N.A.
41.7
22.5
37.9
Protein Similarity:
100
100
64.1
78.2
N.A.
80
35.4
N.A.
77.5
72.1
77.8
67.5
N.A.
N.A.
53.7
36.3
51.9
P-Site Identity:
100
100
100
60
N.A.
73.3
0
N.A.
66.6
33.3
46.6
26.6
N.A.
N.A.
40
13.3
13.3
P-Site Similarity:
100
100
100
73.3
N.A.
86.6
0
N.A.
86.6
53.3
60
66.6
N.A.
N.A.
40
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.5
31.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.1
48.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
54
7
7
0
7
0
7
0
67
7
% A
% Cys:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
47
% C
% Asp:
0
0
0
0
7
0
60
7
0
60
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
7
7
0
0
20
0
0
% E
% Phe:
7
40
14
7
0
0
0
0
7
7
7
0
7
0
0
% F
% Gly:
0
0
0
0
7
0
7
7
7
7
0
7
0
7
20
% G
% His:
7
0
0
0
0
0
0
7
0
7
7
0
0
0
0
% H
% Ile:
7
7
14
7
7
0
7
0
7
0
14
0
0
7
7
% I
% Lys:
40
0
0
27
47
14
0
7
0
0
0
20
0
0
7
% K
% Leu:
14
20
47
14
7
14
0
0
7
7
7
14
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
54
0
0
% Q
% Arg:
20
7
7
27
7
0
0
14
20
0
0
40
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
0
7
0
47
7
0
7
7
% S
% Thr:
0
0
7
0
0
7
7
34
40
0
14
0
0
0
0
% T
% Val:
7
7
7
7
0
14
0
7
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
14
0
14
7
0
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _