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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIK3C3
All Species:
25.45
Human Site:
S211
Identified Species:
50.91
UniProt:
Q8NEB9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEB9
NP_002638.2
887
101549
S211
I
N
E
S
E
K
R
S
S
N
F
M
Y
L
M
Chimpanzee
Pan troglodytes
XP_001142269
757
86303
G139
K
Y
G
M
F
R
Q
G
M
H
D
L
K
V
W
Rhesus Macaque
Macaca mulatta
XP_001082892
887
101541
S211
I
N
E
S
E
K
R
S
S
N
F
M
Y
L
M
Dog
Lupus familis
XP_547599
1258
142817
S515
I
N
E
S
E
K
R
S
S
N
F
M
Y
L
M
Cat
Felis silvestris
Mouse
Mus musculus
Q6PF93
887
101469
S211
I
N
E
S
E
K
R
S
S
N
F
M
Y
L
M
Rat
Rattus norvegicus
O88763
887
101516
S211
I
N
E
S
E
K
R
S
S
N
F
M
Y
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6AZN6
886
101139
S211
I
N
E
S
E
K
R
S
S
N
F
M
Y
L
M
Zebra Danio
Brachydanio rerio
NP_001017550
726
82679
T108
Q
S
A
Q
V
T
L
T
V
W
D
V
Y
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477133
949
107871
S212
N
E
R
E
K
R
M
S
D
Y
M
F
L
M
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94125
1182
136855
C240
F
P
E
E
Q
Y
L
C
V
G
E
S
C
P
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42339
814
93309
I196
M
L
K
S
L
D
T
I
K
E
Q
E
S
T
K
Baker's Yeast
Sacchar. cerevisiae
P22543
875
100903
I222
V
V
F
I
E
R
E
I
M
N
T
Q
M
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
99.5
69.7
N.A.
97.9
98
N.A.
N.A.
N.A.
92
69.7
N.A.
55.9
N.A.
20
N.A.
Protein Similarity:
100
85.3
99.8
69.9
N.A.
98.9
99.4
N.A.
N.A.
N.A.
96.2
76.4
N.A.
71.9
N.A.
37.9
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
N.A.
100
6.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
N.A.
N.A.
100
26.6
N.A.
33.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.8
36.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.4
55.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
9
0
17
0
0
0
0
% D
% Glu:
0
9
59
17
59
0
9
0
0
9
9
9
0
0
0
% E
% Phe:
9
0
9
0
9
0
0
0
0
0
50
9
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
9
0
9
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
50
0
0
9
0
0
0
17
0
0
0
0
0
0
17
% I
% Lys:
9
0
9
0
9
50
0
0
9
0
0
0
9
0
17
% K
% Leu:
0
9
0
0
9
0
17
0
0
0
0
9
9
50
0
% L
% Met:
9
0
0
9
0
0
9
0
17
0
9
50
9
9
50
% M
% Asn:
9
50
0
0
0
0
0
0
0
59
0
0
0
9
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
9
% P
% Gln:
9
0
0
9
9
0
9
0
0
0
9
9
0
0
0
% Q
% Arg:
0
0
9
0
0
25
50
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
59
0
0
0
59
50
0
0
9
9
0
0
% S
% Thr:
0
0
0
0
0
9
9
9
0
0
9
0
0
9
0
% T
% Val:
9
9
0
0
9
0
0
0
17
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% W
% Tyr:
0
9
0
0
0
9
0
0
0
9
0
0
59
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _