KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL13
All Species:
20.91
Human Site:
S496
Identified Species:
57.5
UniProt:
Q8NEE6
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEE6
NP_659469.3
735
83942
S496
C
V
R
L
S
D
A
S
V
M
K
L
S
E
R
Chimpanzee
Pan troglodytes
XP_519284
735
83814
S496
C
V
R
L
S
D
A
S
V
M
K
L
S
E
R
Rhesus Macaque
Macaca mulatta
XP_001085008
735
83692
S496
C
V
R
L
S
D
V
S
V
M
K
L
S
E
R
Dog
Lupus familis
XP_852464
900
102747
S662
C
I
H
L
S
D
A
S
I
V
K
L
S
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDU4
790
90638
S547
C
S
L
L
G
D
S
S
V
I
R
L
S
E
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415966
798
89536
N562
L
R
E
L
N
L
A
N
C
I
H
V
T
D
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34284
466
52046
L234
K
S
L
D
T
L
I
L
R
G
C
E
G
L
T
Sea Urchin
Strong. purpuratus
XP_783241
871
99709
S576
C
V
R
V
T
D
V
S
I
M
K
I
T
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SKK0
628
66570
E396
L
E
S
L
Q
L
E
E
C
H
R
V
T
Q
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
94.9
63.4
N.A.
58.8
N.A.
N.A.
N.A.
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
20.9
33.5
Protein Similarity:
100
99.7
97.4
70.5
N.A.
72.4
N.A.
N.A.
N.A.
62.9
N.A.
N.A.
N.A.
N.A.
N.A.
37.6
53.6
P-Site Identity:
100
100
93.3
73.3
N.A.
60
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
46.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
45
0
0
0
0
0
0
0
12
% A
% Cys:
67
0
0
0
0
0
0
0
23
0
12
0
0
0
0
% C
% Asp:
0
0
0
12
0
67
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
12
12
0
0
0
12
12
0
0
0
12
0
56
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
12
0
0
0
0
12
0
0
12
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
12
12
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
12
0
23
23
0
12
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
0
0
0
56
0
0
0
12
% K
% Leu:
23
0
23
78
0
34
0
12
0
0
0
56
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
45
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
0
0
0
0
23
0
% Q
% Arg:
0
12
45
0
0
0
0
0
12
0
23
0
0
0
56
% R
% Ser:
0
23
12
0
45
0
12
67
0
0
0
0
56
0
0
% S
% Thr:
0
0
0
0
23
0
0
0
0
0
0
0
34
0
12
% T
% Val:
0
45
0
12
0
0
23
0
45
12
0
23
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _