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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL13
All Species:
19.39
Human Site:
S680
Identified Species:
53.33
UniProt:
Q8NEE6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEE6
NP_659469.3
735
83942
S680
K
K
A
A
Q
R
M
S
S
K
V
Q
Q
Q
E
Chimpanzee
Pan troglodytes
XP_519284
735
83814
S680
K
K
A
A
Q
R
M
S
S
K
V
Q
Q
Q
E
Rhesus Macaque
Macaca mulatta
XP_001085008
735
83692
S680
K
K
A
A
Q
R
M
S
S
K
V
Q
Q
Q
E
Dog
Lupus familis
XP_852464
900
102747
S846
K
E
A
A
R
R
M
S
S
M
V
Q
Q
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDU4
790
90638
S731
P
A
A
A
Q
K
M
S
S
V
V
Q
H
Q
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415966
798
89536
N744
L
K
M
L
Y
C
R
N
I
T
K
Q
A
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34284
466
52046
K412
L
R
H
C
K
A
L
K
R
I
D
L
Y
D
C
Sea Urchin
Strong. purpuratus
XP_783241
871
99709
S760
K
P
T
I
V
K
L
S
A
K
I
E
K
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SKK0
628
66570
I574
S
D
K
L
K
L
Q
I
L
S
V
A
G
C
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
94.9
63.4
N.A.
58.8
N.A.
N.A.
N.A.
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
20.9
33.5
Protein Similarity:
100
99.7
97.4
70.5
N.A.
72.4
N.A.
N.A.
N.A.
62.9
N.A.
N.A.
N.A.
N.A.
N.A.
37.6
53.6
P-Site Identity:
100
100
100
80
N.A.
66.6
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
56
56
0
12
0
0
12
0
0
12
12
0
0
% A
% Cys:
0
0
0
12
0
12
0
0
0
0
0
0
0
12
12
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
12
0
0
12
0
% D
% Glu:
0
12
0
0
0
0
0
0
0
0
0
12
0
0
56
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
12
0
0
0
12
12
12
12
0
0
0
0
% I
% Lys:
56
45
12
0
23
23
0
12
0
45
12
0
12
0
0
% K
% Leu:
23
0
0
23
0
12
23
0
12
0
0
12
0
0
12
% L
% Met:
0
0
12
0
0
0
56
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
45
0
12
0
0
0
0
67
45
56
0
% Q
% Arg:
0
12
0
0
12
45
12
0
12
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
0
0
0
67
56
12
0
0
0
0
12
% S
% Thr:
0
0
12
0
0
0
0
0
0
12
0
0
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
0
12
67
0
0
23
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _