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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRFBP1
All Species:
31.21
Human Site:
S274
Identified Species:
62.42
UniProt:
Q8NEF9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEF9
NP_689759.2
429
48634
S274
E
R
F
Y
K
Q
S
S
M
S
E
D
S
D
S
Chimpanzee
Pan troglodytes
XP_001144744
428
48344
S274
E
R
F
Y
K
Q
S
S
M
S
E
D
S
D
S
Rhesus Macaque
Macaca mulatta
XP_001088860
429
48570
S274
E
R
F
Y
K
Q
S
S
M
S
E
D
S
D
S
Dog
Lupus familis
XP_850709
428
48590
M273
R
F
Y
K
Q
S
S
M
S
E
D
S
D
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ91
441
48727
S286
E
R
F
Y
K
Q
S
S
A
S
E
D
S
D
S
Rat
Rattus norvegicus
Q66H19
442
49177
S287
E
R
F
Y
K
Q
S
S
A
S
E
D
S
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508306
383
43035
S223
E
R
F
Y
K
Q
S
S
V
S
E
D
S
G
G
Chicken
Gallus gallus
XP_424408
431
49054
S270
E
R
F
Y
N
Q
T
S
N
S
D
S
D
S
N
Frog
Xenopus laevis
NP_001080631
480
54488
S325
E
R
F
Y
K
H
S
S
S
F
E
D
S
D
G
Zebra Danio
Brachydanio rerio
NP_998213
775
87351
S578
E
E
R
F
H
K
Q
S
S
Q
S
E
D
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121188
294
34508
K145
T
D
S
E
K
N
P
K
R
L
K
N
N
A
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04347
519
60036
S330
D
E
E
P
S
E
A
S
S
D
E
D
D
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
95.8
78.7
N.A.
65.5
65.6
N.A.
43.3
46.6
45.6
27.8
N.A.
N.A.
22.8
N.A.
N.A.
Protein Similarity:
100
97.9
97.1
86.7
N.A.
72.7
73.5
N.A.
55.7
62.1
61.8
38.7
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
80
46.6
73.3
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
93.3
N.A.
86.6
66.6
73.3
33.3
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
17
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
0
0
0
0
0
9
17
67
34
50
17
% D
% Glu:
75
17
9
9
0
9
0
0
0
9
67
9
0
0
0
% E
% Phe:
0
9
67
9
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
25
% G
% His:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
67
9
0
9
0
0
9
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
9
25
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
9
0
0
9
0
0
9
9
0
17
% N
% Pro:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
59
9
0
0
9
0
0
0
0
0
% Q
% Arg:
9
67
9
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
9
9
67
84
34
59
9
17
59
34
42
% S
% Thr:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
67
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _